'Pre|conditioning' restores immune tolerance

Autologous stem cell transplantation for autoimmunity induces ...

... autoimmune disease, data on the mechanisms by which ASCT induces immune tolerance are still very scarce. In this study it is shown that ASCT restores ...

immunotherapeutic combinations for autoimmune disease

... immune components that could be therapeutically targeted to restore a state of immune tolerance. ... pre-existing low-affinity autoreactive ...

LAPIX Therapeutics | Immune System Restoration | Home

... immune tolerance restoration therapies that are non-immunosuppressive. We believe there is a better, gentler way for treating patients with autoimmune diseases.

Archive | Mayo Metabolomics | Vanderbilt University

'Pre-conditioning' restores immune tolerance. A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune ...

Science | Regulatory CD8 T cell network - Mozart Therapeutics

In this context, inhibitory KIR acts as an autoimmune checkpoint, playing a role in regulating immune tolerance. ... Pre-clinical Pharmacology and ...

Conditioning of the immune system by the microbiome - Cell Press

44. Xu, M. ... c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont. Nature. 2018 ...

The impact of GPIbα on platelet-targeted FVIII gene therapy in ...

2bF8 gene therapy restores hemostasis and promotes immune tolerance in HA mice with pre-existing immunity. Author List. Chen J, Schroeder JA, Luo X ...

Sonoma Scores $265 Million to Restore Immune System Balance

Sonoma's two most advanced programs are a novel CAR-based Treg cell therapy for refractory rheumatoid arthritis and a Teff conditioning biologic ...

Decoding the intricacies of immunological tolerance in type 1 diabetes

These therapies aim to restore immunological tolerance and prevent further destruction of beta cells. ... autoimmune condition. Conclusion. As we delve ...

Taming autoimmunity: Translating antigen-specific approaches to ...

... restore immune tolerance. Induction of immune tolerance could be ... conditioning required to ensure complete elimination of the host immune ...

New sights of low dose IL‐2: Restoration of immune homeostasis for ...

... pre-existing autoimmune ... This suggests that IL-2 may be an effective strategy for restoring immune tolerance in SLE patients with infections [ ...

SAT0023 Direct-acting antiviral-based therapy restores immune ...

SAT0023 Direct-acting antiviral-based therapy restores immune tolerance in hepatitis c-induced cryoglobulinemia vasculitis. Free. Loading. C Comarmond,; M ...

MHC-mismatched mixed chimerism restores peripheral tolerance of ...

... restores immune tolerance of peripheral noncross-reactive autoreactive T cells. ... conditioning is able to cure autoimmunity and ...

Current and Future Immunomodulation Strategies to Restore ...

Finally, Treg cellular therapy aims at restoring a tolerogenic Teff:Treg balance by directly increasing the number of Tregs. Immune Tolerance and Autoimmunity.

Emerging antigen-specific therapies for autoimmune diseases

Cell-based approaches to promote or restore tolerance in autoimmune diseases can lead to control the unwanted immune response. Therapies ...

Galectin-1 Restores Immune Tolerance to Liver Transplantation ...

The reaction conditions were as follows: pre-denaturation at 95°C for 30 s, followed by 40 cycles of denaturation at 95°C for 5 s and annealing ...

Anokion Announces New Data from the Phase 1 MoveS-it Study ...

The abstracts include pre-clinical and new clinical data from ... autoimmune diseases by restoring normal immune tolerance. The ...

Anokion Presents Phase 1 MoveS-it Study Data on ANK-700 for ...

The data includes pre-clinical and clinical findings from Anokion's ... autoimmune diseases by restoring normal immune tolerance. The ...

Primary Focus Candidate: Immune Homeostasis - Astellas Pharma Inc.

We are establishing competitive and innovative modalities that can restore immune homeostasis by ... response and induce immune tolerance. Through ...

Regulatory T cells expressing CD19-targeted chimeric antigen ...

CAR-Tregs demonstrated superior immune suppressive capacities in pre-clinical studies. ... restore immune tolerance. Infections, related to an ...