[PDF] Esketamine pretreatment during cesarean section reduced the ...

Intranasal Esketamine for Treatment Resistant Depression - VA.gov

On July 31, 2020, the FDA approved a new indication, depressive symptoms in adults with MDD with acute suicidal ideation or behavior. Because of the risk of ...

Neonatal outcomes when intravenous esketamine is added to the ...

The use of intravenous analgesics during emergency cesarean section may lead to adverse neonatal outcomes. In our study, we investigated ...

Spravato, INN-esketamine - European Medicines Agency

During the study, as part of standard of care treatment, 40% of patients received AD monotherapy, 54% of patients received AD plus ...

Spravato - accessdata.fda.gov

SPRAVATO nasal spray is intended for nasal administration. Esketamine hydrochloride is contained as a solution in a stoppered glass vial within the nasal spray ...

SPRAVATO® (esketamine) nasal spray, CIII - Janssen

Dosing frequency should be individualized to the least frequent dosing to maintain remission/response. 2.3. Depressive Symptoms in Patients with Major ...

Reference ID: 4557859 - accessdata.fda.gov

Hypersensitivity to esketamine, ketamine, or any of the excipients. WARNINGS AND PRECAUTIONS. 5.1 Sedation. In clinical trials, 49% to 61% of SPRAVATO-treated ...

Esketamine pretreatment during cesarean section reduced ... - OUCI

Esketamine pretreatment during cesarean section reduced the incidence of postpartum depression: a randomized controlled trail ... Authors: Shixia Xu; Jiaojiao ...

AusPAR - Spravato - esketamine hydrochloride

During the phase III clinical program patients were assigned SNRI or SSRI as the new oral antidepressant (see section 5.1 Pharmacodynamic ...

First FDA-Approved Antidepressant in a New Class | NEJM

Supplementary Material. Disclosure Forms (nejmp1903305_disclosures.pdf) ... Jianjun Yang,. Esketamine pretreatment during cesarean section reduced the ...

SPRAVATO® - Medsafe

In the clinical trials, the effect of esketamine nasal spray on cognitive functioning was evaluated over time and performance remained stable.

Efficacy of esketamine for perinatal depression: a systematic review ...

Esketamine pretreatment during cesarean section reduced the incidence of postpartum depression: a randomized controlled trial. BMC ...

Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray ...

In both treatment groups, the maximum score reported on the C-SSRS during the double-blind treatment phase was 3. Six of 112 (5.4%) patients ...

Esketamine with tramadol for PCIA after cesarean section | JPR

The second outcomes included the mean NRS scores at rest, sitting, and uterine contraction at 12, 24, and 48 hours postoperatively. The ...

Esketamine Nasal Spray versus Quetiapine for Treatment-Resistant ...

Details about the dosing and administration of the trial treatments are provided in the Supplementary Material S1 section in the Supplementary ...

Management of treatment-resistant depression with esketamine ...

Esketamine nasal spray represents a new treatment paradigm for TRD. This article provides clinical guidance based on the latest evidence and clinical ...

Esketamine: Uses, Interactions, Mechanism of Action - DrugBank

The FDA approved ketamine (Ketalar) in 1970. Esketamine may prove to be a promising treatment for patients diagnosed with major depressive disorder who have not ...

Esketamine for treatment‑resistant depression: A review of clinical ...

Perioperative esketamine administration for prevention of postpartum depression after the cesarean section: A systematic review and meta- ...

Effects of esketamine on analgesia and postpartum depression after ...

The consumption of sufentanil, times of effective press and remediate analgesia at 48 hours after cesarean section, incidence of postpartum depression (PPD) at ...

Phenomenology and therapeutic potential of - ProQuest

PDFDownload PDF ... esketamine treatment for treatment-resistant ... Esketamine pretreatment during cesarean section reduced the incidence of postpartum depression: ...

Esketamine Nasal Spray for Rapid Reduction of Major Depressive ...

There is an unmet need in patients with depression and active suicidal ideation for new therapies that can rapidly bridge the gap until ...