[PDF] The IRE1/XBP1 signaling axis promotes skeletal muscle ...

The ER stress sensor IRE1 interacts with STIM1 to promote store ...

Our findings unveil a direct crosstalk between SOCE and UPR via IRE1, acting as key regulator of ER Ca2+ and proteostasis in T cells and muscles ...

IRE1α protects against osteoarthritis by regulating progranulin ...

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife 10, e73215 (2021). Article ...

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T ...

... IRE1 alpha [p Ser724] Antibody (Novus biologicals,NB100-2323). Mice ... The XBP1 direct target genes of B cell/plasma cell, skeletal muscle ...

IRE1α regulates skeletal muscle regeneration through myostatin ...

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Anirban Roy, Meiricris Tomaz da Silva, Raksha ...

[PDF] TAK1 modulates satellite stem cell homeostasis and skeletal ...

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism · Medicine, Biology. eLife · 2021.

ER stress in skeletal muscle remodeling and myopathies

The PERK/eIF2o signaling axis also inhibits the UPR through inducing gene expression of growth arrest and DNA damage-inducible protein,. GADD34 that promotes ...

Muscle-specific ER-associated degradation maintains ... - JCI Insight

View PDF. Abstract. The ... The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

Article XBP1 Controls Diverse Cell Type- and Condition-Specific ...

The unfolded protein response (UPR) is an evolutionarily conserved signaling pathway that responds to perturbations in endoplasmic reticulum (ER) ...

Confounding Roles of ER Stress and the Unfolded Protein ... - MDPI

... Promotes Skeletal Muscle ... The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia.

ER Ca2+ overload activates the IRE1α signaling and promotes cell ...

Our data establish a causal link between excess Ca 2+ in ER stores and the selective activation of IRE1α-XBP1 axis, underscoring an unexpected role of overload ...

The ER stress sensor IRE1 interacts with STIM1 to promote store ...

... XBP1s–PPARα axis signalling. Nat ... ∙ Richter, E.A.. Ca 2+ -calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise.

Unfolded Protein Response Signaling and Metabolic Diseases

IRE1 and XBP1 (X-box-binding Protein-1) Signaling. Networks and Metabolic ... sponse mediates adaptation to exercise in skeletal muscle through a. PGC-1α ...

Fn14 promotes myoblast fusion during regenerative myogenesis

Skeletal muscle regeneration involves activation of multiple signaling pathways in muscle ... IRE1/XBP1 signaling axis promotes skeletal muscle ...

IRE1 alpha Antibody - SciCrunch

(2021) The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. eLife, 10. Einstein JM, et al. (2021) ...

X-box Binding Protein 1: An Adaptor in the Pathogenesis of ...

Estrogen receptor antagonist fulvestrant inhibits proliferation and promotes apoptosis of prolactinoma cells by regulating the IRE1/XBP1 signaling pathway.

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult ...

IRE1α signaling in satellite cells promotes skeletal muscle regeneration in adult mice. Silencing of IRE1α or XBP1 inhibits myoblast fusion without ...

Breakthrough identification of proteins necessary for muscle ...

More information: Anirban Roy et al, The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism, eLife (2021) ...

The Role of XBP1 in bone metabolism - Frontiers

Annexin A2 regulates unfolded protein response via Ire1-Xbp1 axis in macrophages during P. ... Genome-wide analyses reveal the Ire1a-Xbp1 pathway promotes T ...

MyD88‐mediated signaling intercedes in neurogenic muscle ...

Importantly, myofiber-specific ablation of XBP1 mitigates denervation-induced skeletal muscle atrophy in mice. Collectively, our experiments ...

The Role of Endoplasmic Reticulum Stress in Differentiation of Cells ...

IRE1 signaling pathway. IRE1 and XBP1 play an important role in cell survival and expression of genes associated with myoblast differentiation [ ...