A decade in search of myopia genes

A multiethnic genome-wide analysis of 19420 individuals identifies ...

Introduction: Long axial length (AL) is a risk factor for myopia. Although family studies indicate that AL has an important genetic component with heritability ...

A Bibliometric and Citation Network Analysis of Myopia Genetics

The year 2019 was singled out as a “key year”, taking into account the number of publications that emerged in that year and given that in 2019, ...

Genetics of myopia: Gene finding and beyond

The knowledge on the genetic background of refractive error and myopia has expanded dramatically in the past few years. To date, over 500 genetic loci have ...

Myopia Genetics Report - Contact Lens Update

Almost 200 genes have been identified in common refractive error and syndromic myopia (ie myopia associated with at least one other medical condition – eg ...

IMI – Myopia Genetics Report - UCL Discovery

Several genes for secondary syndromic myopia overlap with those for common myopia. ... A decade in search of myopia genes. Front Biosci. 2010;15: ...

New Genes for Nearsightedness Identified | Johns Hopkins

The researchers recently published their breakthrough in journal Nature Genetics. One of the leading causes of visual impairment worldwide, ...

Genetic evidence for the onset and development of myopia

The genetic factor not only can serve as the independent factor that affects myopia development but also can interact with the environmental ...

Update on the epidemiology and genetics of myopic refractive error

of 15-year-olds have myopia [7], and in adults ... Most genetic discoveries have been for high myopia, with the search for genes underpinning.

5 Onset and Progression of Myopia - The National Academies Press

Evidence is presented on how myopia development may be influenced by genetic factors, visual behaviors such as near work or use of electronic devices, and the ...

Gene Leads to Nearsightedness When Kids Read

“We have known for decades that myopia is caused by genes and their interactions with environmental factors like reading and nearwork, but we ...

Nearsightedness: MedlinePlus Genetics

In some people, nearsightedness improves in later adulthood. For normal vision, light passes through the clear cornea at the front of the eye ...

How did genes causing myopia survive evolution? - Reddit

Myopia is largely environmentally induced. Genes probably effect our sensitivity to the modern environmental effects that produce myopia.

Crosstalk between heredity and environment in myopia: An overview

Currently, it is confirmed that the development of myopia is attributed to the combined action of genes and environmental factors. Thus, elucidating the risk ...

Early onset X‐linked female limited high myopia in three ...

This study describes the clinical spectrum and genetic background of high myopia caused by mutations in the ARR3 gene.

Genetic variants on chromosome 1q41 influence ocular axial length ...

The discovery of chromosome 1q41 as a locus for high myopia in our data is further supported by validation in two independent Japanese cohorts, and the observed ...

Complex Trait Genetics of Refractive Error - JAMA Network

Yap and colleagues noted a prevalence of myopia in 7-year-old children of 7.3% when neither parent was myopic, 26.2% when 1 parent was myopic, and 45% when both ...

A genome-wide analysis of 340 318 participants identifies four novel ...

The prevalence of myopia has increased over the past decades, reaching the highest rates in East Asia (2), but also in Europe (3) and the United States (4).

Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene ...

FK Jacobi, A decade in search of myopia genes., Front Biosci, № 15, с. 359 https://doi.org/10.2741/3625; D Stambolian, Genomewide linkage scan for myopia ...

Approved research - UK Biobank

Myopia has increased rapidly in incidence within the last 3 decades, and population research has linked it to dozens of environmental and genetic risk factors.

IMI Myopia Genetics Report

Both genetic and environmental factors can govern common refractive error, especially myopia. With the introduction of large genome-wide association studies ( ...