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A new era in functional genomics screens


CRISPRi functional genomics in bacteria and its application to ...

1. Przybyla L, Gilbert LA. 2022. A new era in functional genomics screens. Nat Rev Genet 23:89–103.

Publications - Laboratory for Genomics Research

A New Era in Functional Genomics Screens. Przybyla L and Gilbert L. Nature Reviews Genetics. LGR-Collaborator. Covid Publications & Citations. Given the urgent ...

Next Steps for Functional Genomics: Proceedings of a Workshop

... screens and projects to describe gene and protein functions and interactions. ... Charting a Future for Sequencing RNA and Its Modifications: A New Era for ...

A New Era in Functional Genomics Using CRISPR/Cas9 Knockout ...

A New Era in Functional Genomics Using CRISPR/Cas9 Knockout Screening. Abstract. Wenzhi Cai1, Weijing Li, Dan Yang, Huafeng Xie and Jian Huang. In this ...

Spatial Functional Genomics: CRISPR Screens in the Spatial Era

Spatial has emerged as a new frontier in omics analysis and is enabling the molecular and cellular state of tissues to be finely resolved.

The Multinational Coordinated Arabidopsis Thaliana Functional ...

... screens. Overexpression of natural or altered proteins can provide ... Some of the technologies that will be used in the new era of functional genomics ...

Compact CRISPR genetic screens enabled by improved guide RNA ...

A new era in functional genomics screens. Nat Rev Genet. 2022;23(2): ... Measuring error rates in genomic perturbation screens: gold standards for ...

Advancing CRISPR screens to build the "next human cell atlas"

... functional genomics screens in differentiated ... new cell types, and new knowledge to our collective understanding of functional genomics.

Functional Genomics Screening - Sigma-Aldrich

The basic aim of a genomic screen is to understand the emergence of a specific phenotype by modifying gene function in a targeted, purposeful manner. When ...

Genome-scale single-cell CRISPR screens | Nature Reviews Genetics

& Gilbert, L. A. A new era in functional genomics screens. Nat. Rev. Genet. 23, 89–103 (2022). Article CAS Google Scholar · Download references ...

Functional genomics in stem cell models - Frontiers

A new era in functional genomics screens. Nat. Rev. Genet. 23, 89–103. doi:10.1038/s41576-021-00409-w. PubMed Abstract | CrossRef Full Text | Google Scholar.

CRISPR Editing in Stem Cells: New Era in Regenerative Medicine

The first high throughput functional genomics screens in human stem cells were applied in 2014 [7]. Scientists knocked out over 18,000 genes in parallel, and ...

Genetic screens and functional genomics using CRISPR/Cas9 ...

The FEBS Journal is a multidisciplinary molecular biology journal publishing high-quality papers relevant to the molecular, cellular and ...

Higher-order combinatorial chromatin perturbations by engineered ...

In mammalian functional genomics, Cas9-based pooled CRISPR screens ... A new era in functional genomics screens. Nat. Rev. Genet . 23, 89 ...

A new era in functional genomics screens - 科研通

A new era in functional genomics screens. 功能基因组学筛选的新时代. 相关领域. 生物 人类基因组 清脆的 计算生物学 基因 基因组学 功能基因组学 遗传 ...

The Current Situation and Development Prospect of Whole-Genome ...

Przybyla, L.; Gilbert, L.A. A new era in functional genomics screens. Nat. Rev. Genet. 2022, 23, 89–103. [Google Scholar] [CrossRef]; Datlinger, P.; Rendeiro ...

Expanding the flexibility of base editing for high-throughput genetic ...

L.A.. A new era in functional genomics screens . Nat. Rev. Genet ... -H. Pooled CRISPR interference screening enables genome-scale functional ...

CRISPR screen analysis - Galaxy Training!

Genome annotation is a multi-level process that includes prediction of protein-coding genes, as well as other functional genome units such as structural ...

CRISPR-based functional genomics screening in human-pluripotent ...

... screens for complex phenotypes. TSS, transcriptional start site. The rapid evolution of hPSC technology has opened up a new era for disease modeling and ...

CRISPR-based functional genomics screening in human-pluripotent ...

Przybyla, A new era in functional genomics screens, Nat. Rev. Genet., № 23, с. 89 https://doi.org/10.1038/s41576-021-00409-w; Leng, Towards elucidating ...