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A radiobiological model of radiotherapy response and its correlation ...


The Tumor Radiobiology of SRS and SBRT: Are More Than the 5 Rs ...

This is consistent with the predicted loss of tumor response because of tumor hypoxia of single doses compared with fractionated radiation therapy for the same ...

The use of TCP based EUD to rank and compare lung radiotherapy ...

The predicted TCP was computed using EUD model with tissue-specific parameter (a=−10). The assumed radiobiological parameter setting for adjuvant therapy [tumor ...

Comparison of predicted and clinical response to radiotherapy

There is interest in developing models that predict the clinical outcome of radiation therapy. The rationale underlying work in this area is ...

Predicting the Tumour Response to Radiation by Modelling the Five ...

In this study, we used a multi-scale model, which included the five Rs of radiotherapy, to predict the effects of radiation on tumour growth.

CHAPTER 14. BASIC RADIOBIOLOGY - IRSN

The response of an organism to acute total body radiation exposure is influenced by the combined response to radiation of all organs constituting the organism.

Generality Assessment of a Model Considering Heterogeneous ...

... by comparing the model to public data on stereotactic body radiation therapy for non-small cell lung cancer cells. Introduction. Radiation therapy allows for ...

A THEORETICAL INVESTIGATION OF THE RADIOBIOLOGICAL ...

Acknowledgements vi. Abbreviations viii. Abstract ix. 1. Introduction. 1. 2. Radiobiological rationale of high-LET radiotherapy and clinical applications 4.

Challenges in radiobiological modeling: can we decide between LQ ...

To study the dose-response of stage I non-small-cell lung cancer (NSCLC) in terms of long-term local tumor control (LC) after conventional ...

Radiobiological modeling for carbon ion radiotherapy

• 5R's of radiotherapy – radiobiological mechanisms which decrease the radiotherapy response (Withers, 1976). Radiosensitivity. Intrinsic ...

and Radiation Therapy for Non-Small Cell Lung Cancer Patients ...

The Gompertz model was used to describe tumor growth, radiation effect was simulated by the linear-quadratic model with an α/β-ratio of 10, and ...

Second Solid Cancers After Radiation Therapy

therapy techniques need to be able to model the cancer risks from a wide ... biased approach for assessing the shape of the dose-response relationship.

Advances in Radiobiology of Stereotactic Ablative Radiotherapy

Dose-Effect Relationship Models in SABR ... Linear Quadratic Model (LQ Model) is applicable to the calculation of iso-effect doses in treating ...

International Journal of Radiation Oncology, Biology, Physics: Home ...

... the molecular biology underlying cancer and normal tissue radiation response. More. Society Information. ASTRO. Founded in 1958, ASTRO's Opens in new window ...

A Brief Overview of the Preclinical and Clinical Radiobiology of ...

Dose delivery can also be modulated at the microscale, which has led to the development of microbeam radiotherapy (MRT, not to be confused with ...

Radiation Oncology Model | CMS

The Radiation Oncology (RO) Model aims to improve the quality of care for cancer patients receiving radiotherapy (RT) and move toward a simplified and ...

Biological Effects of Radiation - Nuclear Regulatory Commission

... the human body correlate with the relative sensitivity of the cells ... This model is accepted by the NRC since it appears to be the most conservative.

Radiobiology of tissue reactions - ICRP

Based on their time course, early reactions in tissues are defined as those observed within weeks after the (onset of) radiation exposure, e.g. within the first ...

What is Radiation Therapy? | IAEA

Radiotherapy involves using carefully selected doses of ionizing radiation to damage the DNA of cancer cells. The DNA controls how they divide.

Use of the linear-quadratic radiobiological model for quantifying ...

Use of the linear-quadratic radiobiological model for quantifying kidney response in targeted radiotherapy · Cancer BioTherapy and Radiopharmaceuticals 19(3): ...

Adverse Radiation Therapy Effects in the Treatment of Head and ...

Whether used as a single modality or as part of a combined approach, radiation therapy (RT) plays an essential role in the treatment of several ...