A transcriptome|wide association study based on 27 tissues ...

Transcriptome-wide association study identifies novel candidate ...

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration.

Multiple-Tissue Integrative Transcriptome-Wide Association Studies ...

The summary-level TWAS analysis with single brain tissue was first undertaken and then a flexible p-value combination strategy, called summary data-based Cauchy ...

a systematic literature review of transcriptome-wide association ...

This is accomplished by combining genome-wide association study (GWAS) data and tissue-specific gene expression profiles [3]. GWAS is a research ...

Learning from Fifteen Years of Genome-Wide Association Studies in ...

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related ...

Expression- and splicing-based multi-tissue transcriptome-wide ...

Although several transcriptome-wide association studies (TWASs) have been performed to identify genes associated with overall breast cancer ...

Transcriptome-wide association study identifies novel genes ...

A tissue-specific transcriptome-wide association study ... study [24,25,26,27,28]. Reference ... based study. Nutrients 9(6), (2017). R.J. ...

A Genome-Wide Association Study Finds Genetic ... - The Lancet

The SNP-based heritability of broadly-defined headache was 0.211 (standard error=0.015). 3.2 Gene Analysis, Gene-Set Analysis and Tissue Expression Analysis by ...

On the interpretation of transcriptome-wide association studies

den & Weber, B. H. F. A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology ...

Transcriptome-wide association study and eQTL colocalization ...

First, our hypothesis was based on expression data in non-bone tissues and cell types. Recent studies have shown that the direction of eQTL ...

scTWAS Atlas: an integrative knowledgebase of single-cell ...

D.L.. et al. . A gene-based association ... L. A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine.

A transcriptome-wide Mendelian randomization study to uncover ...

intervention27. ... association study to investigate the genetic effects of gene expression across different tissue types. ... A gene-based association method for ...

Transcriptome wide association studies: general framework and ...

... gene-based association method for mapping traits using reference transcriptome data. ... tissue transcriptome-wide association analysis. ... Genet., 27, 1819–1829.

Transcriptome wide association studies: general framework and ...

... associations than the single-tissue based PrediXcan in 103 traits. In their simulation study, PrediXcan exhibited more benefits under a ...

Gene Expression Imputation Across Multiple Tissue Types Provides ...

42. Mishra, A. ∙ Ferrari, R. ∙ Heutink, P. ... Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia. Brain ...

Genome-wide association studies of 27 accelerometry-derived ...

Previous genome-wide association studies (GWAS), based ... wide association analysis using 27 ... For tissue specific analysis, chromatin-based ...

Hippocampal transcriptome-wide association study and ... - PLOS

However, the association of hippocampal gene expression with AD and the underlying neurobiological pathways remain largely unknown. Based on the ...

SUBSET-BASED CROSS-TISSUE TRANSCRIPTOME-WIDE ...

Transcriptome-wide association study (TWAS) is introduced to identify significant expression-trait associations through imputations.

The GTEx Consortium atlas of genetic regulatory effects across ...

... a wide range of both tissues and individuals ... (27). ... wide association study of 21,000 casesand 95,000 controls identifies new risk loci for ...

Novel insight into the aetiology of rheumatoid arthritis gained by a ...

... tissue transcriptome-wide association study ... Gene-based association study. Summary data-based ... 26 Liu et al27 conducted a cross-tissue TWAS for ...

Transcriptome-Wide Association Study Identifies New Candidate ...

8), which is based on GTEx version 7 eQTL data (Supplementary Table S2). To combine S-PrediXcan data across the different brain tissues taking into account ...