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Adenosine A2A receptor


Adenosine receptor - Wikipedia

The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand.

Adenosine A2A Receptor Functional HEK293 Cell Line

Adenosine A2A Receptor Functional HEK293 Cell Line Adenosine A2A receptor (A2aR or ADORA2A) stably expressed in HEK293 cells (NM_000675.5).

Anti-Human Adenosine A2A Receptor (ext.) Antibody - Alomone Labs

Anti-Human Adenosine A2A Receptor (ext.) Antibody (#AAR-007) from Alomone Labs is a highly specific rabbit polyclonal Ab directed against the human protein.

Adenosine A2A receptor antagonist treatment of Parkinson's disease

A 2A receptor blockade might thus alleviate motor abnormalities in parkinsonian patients by limiting the hyperphosphorylation of striatal glutamatergic ...

Definition of adenosine A2A receptor antagonist PBF-509

Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer.

Phase 1 trial of the adenosine A2A receptor antagonist inupadenant ...

Inupadenant is a non brain-penetrant, potent and highly selective small molecule antagonist of the A 2A receptor that remains active even at the high adenosine ...

Adenosine A 2A Receptor Antagonists - Tocris Bioscience

View and buy high purity Adenosine A2A Receptor antagonists from Tocris Bioscience.

The belated US FDA approval of the adenosine A2A receptor ...

Istradefylline is the first non-dopaminergic drug approved by FDA for PD in the last two decades. This approval also provides some important ...

HiTSeeker Adenosine A2A Receptor Cell Line - Innoprot

Innoprot HiTSeeker ADORA2A Cell Line allows to assay compounds, or analyze their capability to modulate ADORA2A. When a ligand binds to the ADORA2A, it ...

Adenosine A1 and A2A Receptors in the Brain - MDPI

The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are predominantly expressed in the brain. Whereas the A2AR has been implicated ...

Adenosine A2 Receptor Antagonists | DrugBank Online

Enprofylline · 5'-nucleotidase, target ; CVT-6883 · Adenosine receptor A2b, target ; Vipadenant · Adenosine receptor A2a, target ; Istradefylline · Cytochrome P450 ...

AAR-002 - Anti-Adenosine A2A Receptor Antibody - Alomone Labs

Anti-Adenosine A2A Receptor Antibody from Alomone Labs is a highly specific rabbit polyclonal Ab directed against mouse ADORA2a. Applications: ICC, IHC, WB.

Role of adenosine A2a receptor in cancers and autoimmune diseases

A2AR receptor is a high-affinity receptor involved in immune regulation among the adenosine receptors. The hypoxic environment in the local ...

Adenosine A2A Receptor Antagonist I, ZM 241385 - Sigma-Aldrich

Adenosine A2A Receptor Antagonist I, ZM 241385 A highly potent, selective, non-xanthine adenosine A2A receptor antagonist (Ki = 800 pM for human adenosine ...

Adenosine A2a Receptor Protein-VLP (ADORA2A) (AA 1-412)

Adenosine A2a Receptor Protein-VLP (ADORA2A) (AA 1-412) ADORA2A Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active

Receptor heteromerization in adenosine A2A receptor signaling

The A2A/D2 heteromeric receptor complex. Evidence has accumulated that intramembrane antagonistic receptor–receptor interactions between ...

Allosteric modulation of the adenosine A2A receptor by cholesterol

Here, we investigate how cholesterol modulates the conformational equilibria and signaling of the adenosine A 2A receptor (A 2A R) in reconstituted ...

Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A ...

In addition, either A2A or A2B blockade with small molecule antagonists can reduce tumor metastasis. Because A2A receptor expression is ...

Adenosine A2A Receptor (extracellular) Polyclonal Antibody, PE

Alomone Labs, LTD Anti-Adenosine A2A Receptor (extracellular) Polyclonal, Catalog # AAR-008-PE-50UL. Tested in Flow Cytometry (Flow) applications.

An Adenosine A2A Receptor Antagonist Improves Multiple ... - eNeuro

In this study, we showed that repeated injection of dopamine D 2 receptor agonist, quinpirole (QNP) elicited two distinct OCD-related behaviors.


Adenosine A2A receptor

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The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it.

Adenosine A2A receptor antagonist

Adenosine A2A receptor antagonists are a class of drugs that blocks adenosine at the adenosine A2A receptor. Notable adenosine A2A receptor antagonists include caffeine, theophylline and istradefylline.