Comedications and potential drug|drug interactions with direct ...

Prevalence of Potential Drug Interactions With Direct-Acting ...

DDI = drug-drug interaction. Table 2. Top medications (≥ 1%) with potential DDIs with nirmatrelvir/ritonavir in pa- tients hospitalized for COVID-19 ...

Drug-drug interactions between antithrombotics and direct-acting ...

Ticagrelor is a weak inhibitor of CYP3A4 and could increase the exposure of drugs with a narrow therapeutic range (Zhou et al., 2011). There are ...

the Swiss HIV Cohort Study, Catia - Sage Journals

Among patients with comedication, 2% (21/1,013) had red-fag interactions (contraindicated) and 59% (597/1,013) had orange-fag interactions (potential dose ...

Drug–drug interactions between direct-acting antivirals and co ...

... or temporary discontinuation of relevant co-medications. Careful assessment for potential DDI before DAA use is mandatory to avoid potential harmful effects.

Real-life data on potential drug-drug interactions in patients with ...

... potential drug-drug interactions (DDIs) between anti-HCV direct-acting antivirals (DAAs) and the comedications used. Aim. To assess the ...

Drug–Drug Interactions of Newly Approved Direct-Acting Antiviral

The newly approved DAA regimens may be prescribed with other drugs simultaneously, increasing the potential of pharmacokinetic interactions.

Italian Real-World Analysis of the Impact of Polypharmacy and ...

The study aims at investigating the impact of polymedication and aging in the prevalence of multiple drug-drug interactions (DDIs) on HCV patients.

Risk of major bleeding among users of direct oral anticoagulants ...

... potential drug–drug interaction. Several ... Furthermore, other comedication, not belonging to the group of direct potential interacting ...

Strategies in patients with atrial fibrillation taking non-vitamin K ...

We agree that in the treatment of patients requiring a combination of drugs with a potential for drug–drug interaction, prudent decision-making on the basis of ...

Drug–Drug Interactions with Direct Oral Anticoagulants

Concomitant drugs that cause drug–drug interactions (DDIs) alter DOAC exposure by increasing or decreasing DOAC bioavailability and/or clearance.

Drug–drug interactions between direct-acting antivirals and co ...

Request PDF | Drug–drug interactions between direct-acting antivirals and co-medications: a territory-wide cohort study | Background The increasing number ...

Evaluating utilization and management of comedications ... - NATAP

Evaluating utilization and management of comedications with potential for drug-drug interactions among patients with chronic hepatitis C

The Korean Journal of Internal Medicine

... comedications, and drug-drug interaction (DDI). It may be ... The proportion of potential drug-drug interaction (DDI) types with direct ...

Analysis of Clinical Drug-Drug Interaction Data To Predict ...

Despite their high potential for drug-drug interactions (DDI), clinical DDI studies of antiretroviral drugs (ARVs) are often lacking, because the full range ...

Annals of Hepatology - Elsevier

Previous studies have evaluated the risk of drug-drug interactions (DDI) in HCV patients receiving pangenotypic direct-acting antivirals (pDAA). This study ...

Drug–Drug Interactions in Italian Patients with Chronic Hepatitis C ...

Among GLE/PIB patients, 2.7% had cardiovascular drugs (all statins) contraindicated while on DAA. The potential DDIs between cardiovascular drugs and SOF/VEL ...

Resource: ART Drug-Drug Interactions - Clinical Guidelines Program

Identify the new drug's potential ... Pharmacodynamic interactions are drug-drug interactions that involve the direct effects of the interacting ...

Drug–drug interaction potential among patients with nonmetastatic ...

Apalutamide and enzalutamide are extensively metabolized by hepatic cytochrome P450 (CYP) enzymes, which may result in pDDIs in patients taking concomitant ...

Proactive monitoring of drug–drug interactions between direct oral ...

When used concomitantly, these potential DDIs can result in increased or decreased DOAC exposure and subsequent increased risk of bleeding or ...

Comorbidities and co-medications in populations with and without ...

Direct-acting anti-viral agents have improved the treatment of chronic ... co-medications because of potential drug–drug interactions. This ...