Comprehensive analysis of biomarkers for prostate cancer based on ...

Clinical utility of current biomarkers for prostate cancer detection

The model using phi had an AUC of 0.77 for overall PCa and of 0.79 for highgrade disease. In a subset of men undergoing repeat prostate biopsy, ...

Emerging biomarkers in the detection and prognosis of prostate ...

The prostate-specific antigen (PSA) is currently the most used tumor marker in the early detection of the prostate cancer (PCa), ...

Current advances of liquid biopsies in prostate cancer - Cell Press

UE is highly accurate at detecting diagnostic biomarkers (see Table 1). A recent study analyzed the mRNA expression of ERG, PCA3, PSMA, CK19, ...

Novel approaches for the identification of biomarkers of aggressive ...

Prostate cancer antigen 3 (PCA3) is a prostate-specific non-coding RNA that was first identified in a comparative transcriptomics study looking ...

Biomarkers for Prostate Cancer: From Diagnosis to Treatment - MDPI

Based on miRNA research, a ratio analysis was employed to enhance the diagnostic accuracy. The urinary miR-1913 to miR-3659 ratio was found to be elevated in ...

Comprehensive biomarker profiles and chemometric filtering of ...

Prostate cancer (PCa) is the most commonly diagnosed cancer in male individuals, principally affecting men over 50 years old, and is the ...

Detection and Prognosis of Prostate Cancer Using Blood‐Based ...

Novel PCa biomarkers, such as the Prostate Health Index (PHI) and the 4Kscore, have been proposed in recent times to improve PSA prediction accuracy.

Genomic biomarkers in prostate cancer - Kornberg

The prostate cancer antigen 3 (PCA3) assay from Progensa is a urine-based, post-DRE, FDA approved test designed to assess the need to re-biopsy men with a ...

Liquid Biomarkers in Prostate Cancer Diagnosis

... based mo- lecular urine analysis for the diagnosis of prostate cancer. ... cancer in four European countries: a comparative modeling study ...

Biomarkers for prostate cancer: prostate-specific antigen and beyond

For determining aggressiveness and predicting outcome, especially in low- or intermediate-risk men, tissue-based multigene tests such as ...

New Biomarkers in Prostate Cancer

Prostate cancer (PCa) is the most commonly diagnosed male cancer in the United States. The prostate-specific antigen (PSA) biomarker has ...

Novel serum proteomic biomarkers for early diagnosis and ...

Background: Prostate cancer (PCa) is one of the most common tumors and the second leading cause of cancer-related death in men. The discovery of novel ...

Biomarkers for prostate cancer detection and risk stratification

Prostate specific antigen (PSA), the most widely used oncologic biomarker, has revolutionized screening and early detection, resulting in ...

Development and Validation of an 18-Gene Urine Test for High ...

Importance Benefits of prostate cancer (PCa) screening with prostate-specific antigen (PSA) alone are largely offset by excess negative ...

Comparative analysis of prostate cancer specific biomarkers PCA3 ...

Early detection of PCa is based on serum. PSA testing and/or abnormal digital rectal examination. (DRE). The gold standard test is still ...

understanding prostate cancer pathology and protein biomarkers for ...

Although PSA remains the gold-standard biomarker for PCa diagnosis and is one of the most widely used blood-based biomarkers in cancer, it ...

Prostate cancer biomarkers - Abcam

Prostate specific antigen ... PSA is the most widely known biomarker for prostate cancer. It is expressed in prostate epithelial cells and ...

Translational Research for Identifying Potential Early-stage Prostate ...

Background/Aim: Prostate cancer (PCa) is one of the most common types of cancer in men. Prostate-specific antigen (PSA) is currently the only biomarker used ...

Urine Biomarkers for Prostate Cancer Diagnosis and Progression

Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could provide more accurate ...

An overview of biomarkers in the diagnosis and management of ...

The use of prostate cancer molecular biomarker analysis of the tumor is now included in guidelines such as in the National. Comprehensive Cancer Network (NCCN) ...