Cross|reactive memory T cells and herd immunity to SARS|CoV|2

Assessment of T-cell Reactivity to the SARS-CoV-2 Omicron Variant ...

Conveniently, T-cell responses are characterized by vast cross-reactivity, and cellular immunity is maintained in the face of mutations that may ...

What about herd immunity? Can cross-reactive immunity help?

Cross-reactive immunity is immunity obtained to one virus because of a previous infection with a different virus, usually one from the same family.

Of Cross-immunity, Herd Immunity and Country-specific Plans

CD4+ T memory cells from sero-negative SARS-CoV-2 unexposed subjects cross-reacted with SARS-CoV-2 and also common HCoVs with respect to epitopes in Spike (S), ...

expert reaction to study looking at cross reactivity of T cells from ...

A study published in Nature Communications looks at cross-reactive memory T cells associated with protection against SARS-CoV-2 infection.

The coevolution of Covid-19 and host immunity

Interestingly, recent data showed the presence of non-spike cross-reactive memory T cells protecting SARS-CoV-2-naïve contacts from infection [56]; these ...

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune ...

This cross-immunity decreased with age. Importantly, we identified an immunodominant Coronavirus peptide epitope (iCope) located within the ...

T-cell response to SARS-CoV-2: kinetic and quantitative aspects ...

Note that, for example, infections with viruses, which evade or suppress innate immune recognition, like HBV or HCV, trigger an induction of ...

New findings on immune response to initial COVID vaccine

More importantly, the researchers found that people who had high numbers of B cells against the ancestral SARS-CoV-2 strain were more likely to ...

Cross-protective immunity following coronavirus vaccination ... - JCI

Characterization of cross-reactive antibody responses with multiple SARS-CoV-2 vaccine modalities. Our experiments above showed that SARS-CoV-2 vaccines induced ...

(PDF) Cross-reactive CD4 + T cells enhance SARS-CoV-2 immune ...

PDF | Cross-reactive T cells aid in the fight There is mounting evidence that immunological memory after infection with seasonal human coronaviruses.

Mucosal vaccine-induced cross-reactive CD8>+> T cells protect ...

Thus, nasally delivered vaccines stimulate mucosal immunity against emerging SARS-CoV-2 strains, and cross-reactive memory CD8+ T cells mediate protection ...

Vaccine-induced systemic and mucosal T cell immunity to SARS ...

351 (β) variant, without lung immunopathology. Thus, induction of systemic and mucosal memory T cells directed against conserved epitopes might ...

Current understanding of T cell immunity against SARS-CoV-2

SARS-CoV-2–recognizing T cells could be detected in SARS-CoV-2–unexposed donors, but the role of these cross-reactive T cells is still in debate ...

Emerging Data Support Lasting COVID-19 Immunity Via T Cells

Antibodies are just one part of the body's immune response. And growing evidence suggests many of us could already have cross-reactive ...

Longitudinal analysis of the evolution of cellular immunity to SARS ...

For immunity that was induced by the virus and not boosted thereafter (i.e., bystander cells), T-cell reactivity peaked 3-5 months after the ...

Memory B and T cells responses differ when induced by SARS-CoV ...

Overall, the results suggested that memory B and T cell responses induced by a booster dose of the mRNA vaccine were different from those ...

expert reaction to study looking at memory T-cells and the immune ...

It appears that some of them had pre-existing memory T cell immunity to a protein involved in replication of the virus, probably induced by ...

Pre-existing memory T cells may only reduce COVID-19 severity, do ...

The memory T cells were found to cross-react with SARS-CoV-2. A team of researchers from La Jolla Institute for Immunology, La Jolla, California ...

Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with ...

However, the immune mechanisms by which this hybrid immunity is generated and maintained are unknown. Whereas genetic variation in spike glycoprotein ...

SARS-CoV-2–specific B- and T-cell immunity in a population-based ...

We then investigated SARS-CoV-2–specific memory B- and T-cell responses by ELISpot and FluoroSpot assays, respectively. We first analyzed cellular immunity on a ...