Dynamic RNA modifications in gene expression regulation

For example, RNA-protein interactions can modulate mRNA and noncoding RNA function. This new appreciation for the potential of RNA has lead to the development ...

Dynamic RNA Modifications in Posttranscriptional Regulation

However, recent studies have revealed that some modifications, like mRNA methylation, can be reversed, and these reversible modifications may play active roles ...

Dynamic RNA Modifications: Roles in Disease and Environmental ...

Dynamic RNA modifications can interpret environmental challenges and respond by altering gene regulation, biological pathways and disease outcomes. Emerging ...

[PDF] Rapid and dynamic transcriptome regulation by RNA editing ...

It is outlined how RNA editing and RNA modification can rapidly affect gene expression, making both processes as well suited to respond to cellular stress ...

mRNA Regulation by RNA Modifications | Annual Reviews

Chemical modifications on mRNA represent a critical layer of gene expression regulation. Research in this area has continued to accelerate ...

Roles of RNA Modifications in Diverse Cellular Functions - Frontiers

m6A mRNA writer, eraser and reader proteins are highlighted in Figure 1. While the writers and erasers can install or remove modifications in RNAs, it is the ...

Gene expression regulation mediated through - ProQuest

These findings strongly indicate dynamic regulatory roles that are analogous to the well-known reversible epigenetic modifications of DNA and histone proteins.

Dynamic RNA Modifications in Gene Expression Regulation - Odisee

Over 100 types of chemical modifications have been identified in cellular RNAs. While the 5′ cap modification and the poly(A) tail of eukaryotic mRNA play ...

Novel insight into the regulatory roles of diverse RNA modifications

Most of these modifications contribute to pre-mRNA splicing, nuclear export, transcript stability and translation initiation in eukaryotic cells.

The dynamic RNA modification 5‐methylcytosine and its emerging ...

With the recent advance in mapping technologies, modifications have been discovered also in mRNA and in less abundant non-coding RNA species.

Emerging role of dynamic RNA modifications during ... - CONICET

Chemical modifications to RNA: a new layer of gene expression · regulation ... Post-transcriptional gene regulation by mRNA · modifications. Nat. Rev. Mol ...

Dynamic RNA Modifications in Posttranscriptional Regulation

We further propose that reversible modifications might occur on tRNA, rRNA, and other noncoding RNAs to regulate gene expression analogous to ...

Dynamic changes in RNA m6A and 5 hmC influence gene ...

RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications ...

Dynamic mRNA modifications: An emerging layer of gene regulation

Biochem (Lond) (2015) 37 (2): 14–18. ... More than 100 different types of chemical modifications are found in cellular RNAs, including ribosomal ...

RNA modifications pathway - Abcam

Over 100 known RNA chemical modifications, including m6A, m1A, ac4C, and m2,2G 1 , can be found on mRNA, tRNAs, rRNAs, and other non-coding RNAs,

Chuan He | University of Chicago Department of Chemistry

Some RNA modifications are dynamic and may have critical regulatory roles analogous to those of protein and DNA modifications. Understanding the scope and ...

Dynamic RNA Modifications in Gene Expression Regulation-期刊

Over 100 types of chemical modifications have been identified in cellular RNAs. While the 50 cap modification and the poly(A) tail of ...

RNA modifications modulate gene expression during development.

Messenger RNA (mRNA) modifications regulate various aspects of mRNA metabolism. For example, N 6-methyladenosine (m6A) affects the translation ...

Dynamic features of gene expression control by small regulatory RNAs

To investigate the steady-state and dynamic potential of such sRNAs, we examine the 2 key parameters characterizing sRNA regulation: the capacity to overexpress ...

RNA modifications in gene expression regulation | Broad Institute

These findings suggest that reversible RNA modification could impact biological regulation analogous to the well-known reversible DNA and histone chemical ...