Engineering Aspects of Protein Interactions and Self|assembly

Infinite Assembly of Folded Proteins in Evolution, Disease, and ...

In this Review, we approach the concept of self-organization by focusing on protein self-assembly. We distinguish between two main types of ...

Growing ecosystem of deep learning methods for modeling protein ...

We discuss recent successes in using representation learning to capture complex features pertinent to predicting protein interactions and interaction sites, ...

Elucidating the assembly of gas vesicles by systematic protein ...

We also examine the tolerance of the GV assembly process to protein mutations and the cellular burdens caused by GV proteins. Clusters of GV protein ...

Approaching infinite affinity through engineering of peptide–protein ...

Unbreakable protein–protein interactions, linked by covalent bonding, provide many opportunities for robust connection of molecular building ...

What are the self-assembling proteins? - Quora

Protein self-assembly is the predominant means of building ... interactions of amino acid side chains with water and with each other.

Self-Assembly of Switchable Protein Nanocages via Allosteric Effect

Protein cages have promising applications in highly efficient gene transportation. Many methods of engineering protein–interface interactions have been ...

Molecular Engineering and Design

Protein-protein interactions · RNA folding and self-assembly · Protein stability, aggregation, and formulation · Molecular binding and allosteric response in drug ...

Protein Self-Assembly: Strategies and Applications - SpringerLink

In the meantime, there have been undergoing unexpected and rapid developments in protein assembly field using supramolecular interaction as ...

Colloidal stability versus self-assembly of nanoparticles controlled ...

Orientational discrimination of biomolecular recognition is exploited here as a molecular engineering tool to regulate nanoparticle self-assembly or ...

Influence of Nonspecific Interactions on Protein Associations

We review the various types of nonspecific interactions between proteins and between proteins and other macromolecules and supramolecular structures that ...

Strategies for engineering self-assembling protein nanostructures ...

Proteins are particularly attractive for molecular assembly due to their inherent molecular recognition and self-assembly capabilities. Advances in the ...

Protein Engineering - Virginia Commonwealth University

This open-source computational tool allows the determination of the most dominant atom-atom interactions among the residues of protein-protein binding partners.

Improving split reporters of protein-protein interactions through ...

Our study allowed the identification of a system with improved properties and enabled a better understanding of the molecular features ...

Design of protein-binding proteins from the target structure alone

The design of proteins that bind to a specific site on the surface of a target protein using no information other than the three-dimensional ...

Biotechnology Advances - University of Delaware

Conditional control of protein interactions enables programmable assembly, colocalization, and spatial organization of proteins inside cells.

Synthetic Protein Circuits and Devices Based on Reversible ... - MDPI

Protein-protein interactions (PPIs) contribute to regulate many aspects of cell physiology and metabolism ... self-assembly control in E. coli through ...

Driving forces of self-assembly in protein-polymer bioconjugates

Partial structure factor analysis and subsequent inverse Fourier transformation showed that protein-polymer interactions could be quantified and understood in ...

Lab develops protein assembly road map for gas vesicles

Bioengineers developed a road map for the protein-protein interactions that give rise to gas vesicles, naturally occurring nanobubbles with ...

Protein–protein interaction and quaternary structure | Cambridge Core

Specific non-covalent interactions stabilize the structure of macromolecular assemblies, exemplified in this review by oligomeric proteins and the capsids of ...

Supramolecular assembly of protein building blocks: from folding to ...

The basic principle that forms these hierarchical structures is protein self-assembly. A single building block is sufficient to create ...