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Evaluation and diagnostic value of next‐generation sequencing ...


Methodological Issues in Assessing the Economic Value of Next ...

Clinical use of next-generation sequencing (NGS) tests has been increasing, but few studies have examined their economic value. Several studies have noted that ...

Targeted next-generation sequencing has incremental value ... - PLOS

This study demonstrates the incremental diagnostic value of NGS in patients with an initial inconclusive diagnosis.

A systematic review and meta-analysis - Sequencing - ResearchGate

Conclusion This systematic review and meta‐analysis found NGS had higher sensitivity and diagnostic accuracy but slightly lower specificity than ...

Higher diagnostic value of next-generation sequencing versus ...

NGS had higher sensitivity and diagnostic accuracy but slightly lower specificity than culture, and it was suggested NGS may have the potential to be a new ...

Assessing the Value of Next-Generation Sequencing Tests in a ...

NGS-based testing is a technology in evolution—evolving from completion of the human genome mapping in 2003, which at that time, relied on laborious older ...

Clinical diagnostic value of targeted next‑generation sequencing for ...

Assays using next-generation sequencing (NGS) technology have potential to improve diagnosis of infectious diseases. NGS allows for sequencing ...

Importance of Next-Generation Sequencing in Myeloid Molecular ...

NGS offers distinct advantages for risk stratification. Given the sheer number of genetic abnormalities that must be evaluated, a multi-gene NGS panel can ...

Valuing DNA sequencing (NGS/CGP) in oncology diagnostics - LSE

of diagnostic genetic testing including NGS and its application of CGP reflecting the preferences and values of various stakeholders. This project was funded ...

Defining the Clinical Value of a Genomic Diagnosis in the Era of ...

Defining the Clinical Value of a Genomic Diagnosis in the Era of Next-Generation Sequencing ... Abstract. As with all fields of medicine, the ...

Diagnostic Significance of Targeted Next-Generation Sequencing in ...

The diagnostic efficacy of tNGS was higher than that of conventional assays, as shown by its AUC of 0.794, which was significantly better than ...

The clinical value of next-generation sequencing integration within ...

Second generation sequencing typically has short sequence reads leading to sequencing gaps, alignment issues due to repetitive regions/ ...

The Diagnostic Value of Blood Next-Generation Sequencing in Early ...

To determine the diagnostic value of blood next-generation sequencing (NGS) in early surgical site infection after spine surgery.

What is Next-Generation Sequencing (NGS) Technology?

Next-generation sequencing (NGS) is a technology for determining the sequence of DNA or RNA to study genetic variation associated with diseases or other ...

Can We Demonstrate the Value of Next-Generation Sequencing ...

Emerging data suggest that multigene next-generation sequencing (NGS)-based testing approaches enable more efficient use of healthcare resources.

Review of Clinical Next-Generation Sequencing - Allen Press

Next-generation sequencing (NGS) is a technology being used by many laboratories to test for inherited disorders and tumor mutations.

Diagnostic value of DNA or RNA-based metagenomic next ...

RNA-mNGS may reduced the misdiagnosis rate of bacterial and fungal pathogens in LRTIs.Compared to RNA-mNGS, DNA-mNGS may could improve the ...

An umbrella review of the diagnostic value of next-generation ...

An increasing number of systematic reviews (SRs) have evaluated the diagnostic values of next-generation sequencing (NGS) in infectious ...

Clinical diagnostic value of targeted next‑generation sequencing for ...

Clinical diagnostic value of targeted next‑generation sequencing for infectious diseases (Review) ... Authors: Qiuyue Chen; Jie Yi; Yiwei Liu; Chenglin Yang ...

a systematic review and meta-analysis

Introduction: Systematic evaluation of the diagnostic value of next generation sequencing (NGS) in sepsis etiology. Methodology: We ...

Evaluation of targeted next-generation sequencing for detection of ...

We conducted a proof-of-concept study of targeted NGS to detect 62 common equine bacterial, viral, and parasitic pathogens in clinical samples.