Functional Annotation of the Human Genome

Genome annotation: From human genetics to biodiversity genomics

This piece briefly reviews the basics of protein-coding gene prediction, discusses challenges in finalizing annotation of the human genome,

Structural and Functional Annotation of the Human Genome for ...

Now that the human genome has been sequenced, the next step is to undertake the complete structural and functional annotation of genes associated with.

Functional Annotation and Analysis of Genetic Variants - IEEE Xplore

Abstract: The process of functional annotation of human genetic variants is important for some significant biomedical tasks like ...

Comprehensive Functional Annotation of Metagenomes and ...

Comprehensive functional annotation is crucial in identifying disease-causing functional changes in proteins, detecting antibiotic resistance genes (3, 4), and ...

Toward a Functional Annotation of the Human Genome Using ...

The artificial transcription factor-based random genome perturbation method thus provides a novel functional genomic tool for annotation and classification of ...

A computational interactome and functional annotation for the ... - eLife

We show, using Gene Set Enrichment Analysis (GSEA), that predicted interaction partners can be used to annotate a protein's function. We provide ...

Functional annotation of human long noncoding RNAs using ...

Using chromatin conformation and Cap Analysis of Gene Expression (CAGE) data in 18 human cell types, we systematically located genomic regions ...

Annotation of functional variation in personal genomes using ...

We have developed a novel approach and database, RegulomeDB, which guides interpretation of regulatory variants in the human genome. Reg-. ulomeDB includes high ...

Annotating the Function of the Human Genome with Gene Ontology ...

In this study, we presented a framework named Gene2Function to annotate Gene Reference into Functions (GeneRIFs), in which each functional description of ...

Functional Annotation and Enrichment Analysis Service

Functional annotation is the process of attaching biological information to sequences of genes or proteins. The basic level of annotation is using sequence ...

Genome annotation with Funannotate - Galaxy Training!

Genome annotation is a multi-level process that includes prediction of protein-coding genes, as well as other functional genome units such ...

Human assembly and gene annotation - Ensembl

The Ensembl human gene annotations have been updated using Ensembl's automatic annotation pipeline. The updated annotation incorporates new protein and cDNA ...

Functional Annotation of Animal Genomes (FAANG)

This website represents the online home of the Functional Annotation of ANimal Genomes (FAANG) consortium. We aim to identify all functional elements in ...

Sequence Organization and Functional Annotation of Human ...

2003. Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes. Nucleic Acids ...

Defining functional DNA elements in the human genome - PNAS

The resulting genome-wide data reveal sites of biochemical activity with high positional resolution and cell type specificity that facilitate studies of gene ...

Genome annotation and functional annotation: Connecting genes to ...

However, merely deciphering the sequence of DNA was just the beginning. Understanding the function of each gene within the genome was the next crucial step.

Editorial: Intelligent Systems for Genome Functional Annotations

Functional annotation of an entire genome is critical to the understanding of any biological process or pathway. Yet, large parts of the human ...

Functional annotation of the animal genomes: An integrated ... - PLOS

Functional annotation of a reference genome provides critical information that pertains the tissue-specific gene expression and regulation. Non-model organisms ...

MGI-Mouse Functional Annotation using the Gene Ontology (GO)

Gene Ontology annotation is a manually or automatically assigned text file containing the following information: Gene name, symbol; Gene Ontology term ...

Genomic data mining for functional annotation of human long ...

Recent results from our studies and those of other groups indicate that genomic data mining can give insights into lncRNA functions and provide ...