Hypertension pharmacogenomics

Pharmacogenomics of hypertension in chronic kidney disease

ABSTRACT. Background Patients with chronic kidney disease (CKD) often have uncontrolled hypertension despite polypharmacy. Pharmacogenomic drug- ...

Pharmacogenomics of antihypertensive drugs: Rationale and ...

Conclusions. Pharmacogenetic-guided therapy holds clinical potential for hypertension, but the literature in the field is limited. This trial will add ...

PHARMACOGENOMICS OF HYPERTENSION

The aim of this pharmacogenomic (PGX-HT) study is to test the effect of genetic profiles of hydrochlorothiazide (HCTZ) and perindopril (Peri) in patients with ...

Pharmacogenomics considerations in the control of hypertension

We also describe a new Phase II drug that targets two specific hypertension predisposing mechanisms. Keywords: antihypertensive drug ...

Hypertension pharmacogenomics - Enlighten Publications

Hypertension is the most important modifiable risk factor for cardiovascular disease. Despite the plethora of effective pharmacological ...

PHARMACOGENOMICS-GUIDED DRUG THERAPY FOR ...

High-throughput targeted sequencing panel was designed to detect efficacy and adverse-related genes of 24 commonly used antihypertensive drugs ( ...

The Pharmacogenomics of Anti-Hypertensive Therapy - MDPI

Hypertension pharmacogenomics seeks to find genetic predictors of response to drugs that lower blood pressure and to translate this knowledge into clinical ...

Exploring Pharmacogenetic Testing for Hypertension Management ...

Furthermore, initiatives like the Pharmacogenomic Examination and Management of hypertension patients in China based on antihypertensive ...

Pharmacogenomic studies of hypertension

Hypertension Pharmacogenomics of hydro-chlorothiazide (MIHYPHCTZ), the Campania Salute ... Antihypertensive; blood pressure; pharmacogenomics ...

Pharmacogenomics of antihypertensive drugs: past, present and ...

Hypertension pharmacogenomics holds the promise of leading to individualized drug treatment approaches for the approximately 1 billion individuals worldwide ...

A genome-wide, placebo-controlled cross-over study, using four ...

Pharmacogenomics of hypertension: A genome-wide, placebo-controlled cross-over study, using four classes of antihypertensive drugs. Timo P. Hiltunen, Kati M ...

Pharmacogenomics in hypertension - Preprints.org

There are multiple choices of drugs and drug classes to treat hypertension, and yet the rate of successful blood pressure control is ...

Pharmacogenomics and hypertension: Current insights - Mendeley

To address the effects of genetic polymorphisms on blood pressure responses to the antihypertensive drug classes, studies have applied candidate genes and ...

Pharmacogenomics of Hypertension Treatment - OUCI

Genetic factors not only affect blood pressure (BP) elevation but also contribute to inter-individual variability in response to antihypertensive treatment.

(PDF) Pharmacogenomics And Hypertension: Current Insights

To address the effects of genetic polymorphisms on blood pressure responses to the antihypertensive drug classes, studies have applied candidate ...

Pharmacogenomics of hypertension: a realizable goal?

Pharmacogenomics of hypertension: a realizable goal? It is common clinical ... Only 22 out of 56 (39 %) individuals achieved the target blood pressure with their ...

Pharmacogenomics assists in controlling blood pressure ... - Frontiers

Pharmacogenomics, as a tool for personalized healthcare, helps in determining the optimal drug treatment based on the genome of individual patient.

Pharmacogenetics: Therapeutic regimen in hypertension

Pharmacogenetics in hypertension is a growing field that seeks to personalize the treatment of this common cardiovascular condition. By ...

Exploring Pharmacogenetic Testing for Hypertension Management ...

Back Article · [12], Pharmacogenomic Examination and Management of hypertension patients in China based on antihypertensive efficacy and adverse reactions. 2022.

Pharmacogenomics and the Concept of Personalized Medicine for ...

Hypertension poses a significant global burden due to low adherence to antihypertensive medications. Hypertension treatment aims to bring ...