IRE1/XBP1 signaling promotes skeletal muscle regeneration ...

bioRxiv on X: "IRE1/XBP1 signaling promotes skeletal muscle ...

IRE1/XBP1 signaling promotes skeletal muscle regeneration through a cell non-autonomous mechanism https://t.co/nXRvsSATly #bioRxiv.

IRE1α protects against osteoarthritis by regulating progranulin ...

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife 10, e73215 (2021). Article ...

The PERK arm of the unfolded protein response regulates satellite ...

Genetic ablation of XBP1 in satellite cells does not affect skeletal muscle regeneration in adult mice. In response to ER stress, IRE1 becomes activated by ...

IRE1α–XBP1 signaling in leukocytes controls prostaglandin ...

IRE1α–XBP1 signaling in leukocytes promotes pain behaviors ... The underlying muscle ... Chen, Pharmacological targeting of MYC-regulated IRE1/XBP1 ...

Skeletal muscle regeneration discovery paves the way for targeted ...

"During muscle regeneration, IRE1 augments ... In this study, they found that IRE1α/XBP1 signaling axis also plays an important cell autonomous ...

Cell signaling in canine skeletal muscle cells | Sigma-Aldrich

... muscle groups. Here. The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

Fn14 promotes myoblast fusion during regenerative myogenesis

(2021) The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife 10: e73215. doi ...

UH College of Pharmacy Unveils Breakthrough in Skeletal Muscle ...

... signaling protein, is essential for myoblast fusion during muscle formation and growth. “During muscle regeneration, IRE1 augments the activity of X-box ...

The ER stress sensor IRE1 interacts with STIM1 to promote store ...

IRE1 deficiency reduces. T cell activation and human myoblast differentiation. In turn, STIM1 deficiency reduces IRE1 signaling after store ...

Muscle-specific ER-associated degradation maintains ... - JCI Insight

... growth phase of postnatal ... The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required ...

Abstract: In skeletal muscle, myoblast differentiation results in the formation of multinucleated myofibers. Although recent studies have ...

ER stress in skeletal muscle remodeling and myopathies

The PERK/eIF2o signaling axis also inhibits the UPR through inducing gene expression of growth arrest and DNA damage-inducible protein,. GADD34 that promotes ...

The Role of XBP1 in bone metabolism - Frontiers

... XBP1 signaling pathway in bone ... regeneration-promoting role, but their mechanisms ... The Ire1alpha-Xbp1 pathway is essential for osteoblast differentiation ...

IRE1α arm of unfolded protein response in muscle-specific TGF-β ...

... skeletal muscle regeneration ... Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory ...

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult ...

IRE1α signaling in satellite cells promotes skeletal muscle regeneration in adult mice. Silencing of IRE1α or XBP1 inhibits myoblast fusion without ...

Journal Pre-proof - ScienceDirect.com

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife 10, e73215. 10.7554/eLife ...

Confounding Roles of ER Stress and the Unfolded Protein ... - MDPI

In contrast, knockdown of XBP1 ... Promotes Skeletal Muscle Atrophy by Forming ... signaling activates growth-control genes during overload-induced ...

The ER stress sensor IRE1 interacts with STIM1 to promote store ...

∙ Richter, E.A.. Ca 2+ -calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise. J. Physiol. 2006; 574:889- ...

Constitutive Role for IRE1α-XBP1 Signaling Pathway in the Insulin ...

... promotes the nuclear translocation (activation) of XBP1 (21, 22). ... Chronic Hyperinsulinemia Increases Myoblast Proliferation in Fetal Sheep Skeletal Muscle.

MyD88‐mediated signaling intercedes in neurogenic muscle ...

... IRE1/XBP1 pathway in skeletal muscle. ... signaling axis mediates ... skeletal muscle strength, maintains mass, and promotes regeneration.