Incretin Therapies for Patients with Type 2 Diabetes and Chronic ...

Incretin-based Therapies for Type 2 Diabetes—Comparisons ...

Sitagliptin showed non-inferiority to glipizide as an adjunct to ongoing metformin treatment in a 52-week study that included 1,172 patients ( ...

Incretin-based therapies for type 2 diabetes mellitus - ResearchGate

Incretin-based drugs, such as glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase 4 inhibitors, are now routinely used to treat type 2 ...

European Journal of Internal Medicine

Efficacy and Safety of Incretin-Based Therapies in Patients with Type 2. Diabetes Mellitus✩. Matthew P. Gilbert, DO, MPH, Richard E. Pratley, MD ⁎. Diabetes ...

Incretin Therapies for Patients with Type 2 Diabetes and Chronic ...

Since the early 2000s, an influx of novel glucose-lowering agents has changed the therapeutic landscape for treatment of diabetes and diabetes-related ...

Incretins: What Are They, and How Are They Beneficial? - GoodRx

Incretin mimetics are medications that mimic incretin hormones. They're currently approved for Type 2 diabetes or chronic weight management in certain people.

Integrating Incretin-Based Therapy into Type 2 Diabetes Management

2 Of the in- cretin hormones, glucagon-like peptide-1 (GLP-1) is particularly important as postprandial levels of GLP-1 are decreased in patients with impaired ...

Incretin System in the Pathogenesis of Type 2 Diabetes and the ...

Since malfunction of incretin hormones has been found to have role in T2 DM pathogenesis, incretin based therapies have been developed. Incretin effect, ...

[PDF] Efficacy and safety of incretin therapy in type 2 diabetes

Careful postmarketing surveillance for adverse effects, especially among the DPP4 inhibitors, and continued evaluation in longer-term studies and in ...

Safety and benefit of incretin-based therapies in patients with type 2 ...

Among novel antidiabetic agents are the incretin-based therapies (IBTs), working on the gastrointestinal-hepatopancreatic-brain axis through the modulation of ...

Incretin-based therapy of metabolic disease | Ugeskriftet.dk

Evidence shows that the secretion of incretin hormones may be impaired in some patients (particularly secretion of GLP-1 in obese individuals), ...

Incretin-Based Therapies for Diabetic Complications - MDPI

Incretin dynamics are impaired in type 2 diabetes. Clinical studies have shown that the incretin effect in diabetic patients is reduced compared to that in ...

Comparison of efficacy between incretin-based therapies for type 2 ...

Incretin based therapies are available as either incretin mimetics (also called GLP-1 agonists) or incretin enhancers (DPP-4 inhibitors).

Incretin-based Therapies (Glucagon-like Peptide-1 Receptor ...

The treatment algorithm for pharmacological treatment of type 2 diabetes in the 2008 Canadian Diabetes Association clinical practice guidelines positioned ...

Recent advances in incretin‐based therapies - Wiley Online Library

The role of the incretin system in the pathophysiology of diabetes was confirmed with data demonstrating a reduced incretin effect in subjects ...

Clarifying the Role of Incretin-Based Therapies in the Treatment of ...

Incretin dysfunction, along with a number of other defects, has been implicated in contributing to the pathogenesis of type 2 diabetes mellitus (T2DM).

Incretin-Based Therapy for Type 2 Diabetes Mellitus: Pancreatic and ...

... chronic neurodegenerative diseases such as Parkinson disease and ... type 2 diabetic patients and healthy subjects. J Clin Endocrinol Metab. 2003 ...

Enhancing treatment success with incretin-based therapies - ACOFP

Incretin;. Type 2 diabetes;. Hyperglycemia;. Patient adherence;. Hypoglycemia;. GLP-1 receptor agonists. Adding glucagon-like peptide-1 (GLP-1) receptor ...

The changing landscape of type 2 diabetes: the role of incretin ...

The incretin-based therapies can favorably impact some underlying elements in T2DM pathophysiology, including glucagon hypersecretion, rapid gastric emptying, ...

Glucagon-like peptide 1-based therapies for the treatment of type 2 ...

(See "Management of hyperglycemia in patients with type 2 diabetes and advanced chronic kidney disease or end-stage kidney disease".) In these ...

The role of incretin therapy at different stages of diabetes. - Abstract

The addition of DPP-4 inhibitors or incretin mimetics to metformin is of particular benefit in patients who need an increase in endogenous insulin secretion, ...