Influenza|A mediated pre|existing immunity levels to SARS|CoV|2 ...

Influenza A Virus Vaccination: Immunity, Protection, and ... - MDPI

For cellular responses, it has been established that the presence of both pre-existing influenza virus specific T cells and cytokine producing effector T cells ...

Roadmap | CIDRAP - University of Minnesota

Antigenic drift results in influenza virus variants that are no longer neutralized by immune responses generated through prior natural infection or strain- ...

Pre-existing immunity against swine-origin H1N1 influenza ... - PNAS

Using data from the Immune Epitope Database, we found that only 31% (8/26) of B-cell epitopes present in recently circulating H1N1 strains are conserved in the ...

Human Serology & Flu | Influenza (Flu) - CDC

Just as CDC uses seroprevalence studies to assess population immunity against seasonal influenza viruses, CDC also uses the same seroprevalence ...

Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective ...

Although HI titers and levels of neutralizing antibodies are still useful indicators of specific immunity against influenza, the measurement of the cross- ...

The role of cell-mediated immunity against influenza and its ...

The first infection with an influenza virus induces an immune response that involves the mobilization and cooperation of numerous components of the immune ...

Hemagglutinin Stalk-Specific Fc-Mediated Functions Are Associated ...

Pre-existing ADCP scores ≥250 reduced the odds of A/H1N1 infection (odds ratio [OR], 0.11; P = .01) with an 83% likelihood of risk reduction.

Atypical antibody responses to influenza - Journal of Thoracic Disease

Exposure to influenza virus hemagglutinin (HA) and neuraminidase (NA) antigen, either through vaccination or infection, induces an antibody response able to ...

A replication-competent adenovirus-vectored influenza vaccine ... - JCI

Taken together, these data suggested that, although most participants were able to be infected via the URT, preexisting immunity limited the period of virus ...

Heterosubtypic cross-reactivity of HA1 antibodies to influenza A, with ...

Epidemics of influenza A vary greatly in size and age distribution of cases, and this variation is attributed to varying levels of pre-existing immunity.

The immunology and immunopathology of COVID-19 | Science

529 (Omicron), have mutations that render them less susceptible to vaccine-mediated and infection-acquired immunity. It is less apparent whether ...

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Timing of Assessment of Humoral and Cell-Mediated Immunity after ...

The incidence of influenza may return to pre-COVID-19 levels during the 2024/2025 season. It is likely that annual seasonal influenza epidemics will continue to ...

The protective potential of Fc‐mediated antibody functions against ...

influenza virus, preinfection or baseline levels of cross-reactive Fc-functional HA antibodies (Abs; blue line) are present as a result of prior influenza virus ...

Investigation of CD4 and CD8 T cell-mediated protection against ...

Every fold increase in pre-existing seasonal H1N1 influenza A virus (sH1N1)-specific CD4 and CD8 T cells was associated with 28% (95% CI 11%, 41 ...

An underappreciated correlate of cross-protection against influenza?

Upon influenza virus infection, virus-specific antibody and T cell responses are induced. Virus-neutralizing antibodies directed to the viral HA are considered ...

Harnessing preexisting influenza virus-specific immunity increases ...

We observed significantly increased SARS-CoV-2 neutralizing antibodies in mice with PR8 immunity compared to mice without preexisting PR8 immunity.

Pre-existing immunity to influenza viruses through infection ... - bioRxiv

The early stages of influenza virus ... The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral ...

Innate and acquired humoral immunities to influenza virus are ...

The host-derived (IgMb) antiviral antibody levels follow the pattern for a typical primary response, which peaks around day 10 after infection (Fig. 5). The ...

Both Humoral and Cellular Immunity Limit the Ability of Live ...

Increasing the level of escape from Ab enabled boosting of pre-existing TRM, but we were unable to generate de novo Sendai virus NP+ CD8+ TRM ...