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Initial treatment of CLL


How We Treat Chronic Lymphocytic Leukemia

Several oral targeted agents have also recently been approved for treatment of CLL. These include ibrutinib, idelalisib, venetoclax, acalabrutinib, and ...

iwCLL guidelines for diagnosis, indications for treatment, response ...

Assessing time to first treatment in early chronic lymphocytic leukemia (CLL): a comparative performance analysis of five prognostic models with inclusion ...

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic ...

1 deletion (typically 5 to 10% of previously untreated patients with CLL). Ibrutinib substantially improved overall survival, with an overall ...

Q&A: Early Treatment of CLL - OncLive

Richard R. Furman, MD, and Nitin Jain, MD, share insight on the evolving treatment landscape of CLL, particularly for treatment in early line settings.

Initial treatment of CLL: integrating biology and functional status

Chemoimmunotherapy (CIT) has been the standard first-line therapy for CLL. Age and comorbidities can help decide which patients may benefit from a CIT approach.

Watch and Wait - Leukemia & Lymphoma Society

Several studies have confirmed that patients with early-stage CLL do not benefit from the use of alkylating agents or aggressive chemotherapy, and these ...

Chronic lymphocytic leukemia - Diagnosis and treatment - Mayo Clinic

Chemotherapy. Chemotherapy is a drug treatment that kills quickly growing cells, including cancer cells. Chemotherapy treatments can be ...

CLL: When to Watch and Wait and When to Start Treatment

There is no evidence that early treatment is of any benefit in chronic lymphocytic leukemia (CLL). Treatment should be based on what is ...

Chronic Lymphocytic Leukemia: Treatment Options - LRF

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Treatment Options · Acalabrutinib (Calquence) · BR (bendamustine [Treanda] and rituximab [Rituxan]) · CG ( ...

First treatment for chronic lymphocytic leukemia (CLL) - Healthline

If you have early CLL that's not causing symptoms or progressing quickly, your doctor may recommend watchful waiting to manage it. They won't ...

What to Expect From CLL Treatment - WebMD

Targeted drug therapies are often the first-line treatment – that is, the first approach your doctor will try – for advanced or symptomatic CLL.

Treatment for Chronic Lymphocytic Leukaemia (CLL)

If you need treatment, it usually includes targeted therapy, with or without immunotherapy (monoclonal antibodies). Chemotherapy is less commonly used.

Chronic Lymphocytic Leukemia (CLL) Guidelines

The guidelines are in agreement that patients with early-stage CLL should not be treated with chemotherapy until they become symptomatic or display evidence of ...

[PDF] Initial treatment of CLL: integrating biology and functional status.

Age and comorbidities can help decide which patients may benefit from a CIT approach, and the combination treatment of chlorambucil and obinutuzumab or ...

Treating Chronic Lymphocytic Leukemia - American Cancer Society

Who treats CLL? ; hematologist: a doctor who treats blood disorders. ; radiation oncologist: a doctor who treats cancer with radiation therapy ; medical oncologist ...

Chronic lymphocytic leukaemia - Treatment - NHS

The main treatments for chronic lymphocytic leukaemia are targeted medicines and chemotherapy. You may just have a targeted medicine on its own or combined ...

New and Breakthrough Treatment Options for CLL - Healthline

Monoclonal antibody therapies · rituximab (Rituxan): targets CD20, often used with chemotherapy or targeted therapy as part of the initial treatment or in the ...

Early Intervention in Asymptomatic Chronic Lymphocytic Leukemia

Early intervention refers to the administration of anti-CLL therapy to patients who otherwise would be under observation alone owing to a lack of symptoms ...

Approaches to Chronic Lymphocytic Leukemia Therapy in the Era of ...

Ibrutinib, a Bruton's tyrosine kinase inhibitor, has approval by the U.S. Food and Drug Administration for the initial treatment of CLL and for relapsed disease ...

Chronic lymphocytic leukemia treatment - The Leukaemia Foundation

Many people with CLL, particularly in the early stages of disease, have no symptoms and don't require any treatment. Instead the doctor may ...