Landscape of Dysregulated Placental RNA Editing Associated with ...

Pre-eclampsia intronic polyadenylation enriched in VEGFA-VEGFR2 ...

Yang, X., et al., Landscape of Dysregulated Placental RNA Editing Associated With Preeclampsia. 38. Hypertension, 2020. 75(6): p. 1532-1541 ...

Distinct placental molecular processes associated with early-onset ...

Methods: We carried out RNA-seq on 65 high-quality placenta samples, including 33 from 30 patients and 32 from 30 control subjects, to search for dysregulated ...

Three transposable elements exhibiting differential expression in ...

Yang, Landscape of dysregulated placental RNA editing associated with preeclampsia, Hypertens. Dallas Tex 1979 75 (2020) 1532–1541, https ...

Genome-wide identification of transcriptional enhancers during ...

We hypothesized that mapping sites of transcriptional enhancer activity and associated changes in gene expression across gestation in human placenta tissue ...

Placenta Transcriptome Profiling in Intrauterine Growth Restriction ...

RNA-Seq data were used to profile protein-coding genes, detect alternative splicing events (AS), single nucleotide variant (SNV) calling, and RNA editing sites ...

Multi-level remodeling of transcriptional landscapes in aging and ...

This emerging class of RNAs has recently been gaining traction in the aging field, notably because many circRNAs have been observed to be differentially ...

Placenta in Early-Onset Severe Preeclampsia

the RNA (Figure E-F). These enriched ac4C-modified RNA-related genes. 193 ... Landscape of Dysregulated Placental RNA Editing. 510. Associated With ...

Long non-coding RNAs in placental development and disease - Basak

Ever-increasing amount of RNA sequencing data is expanding the lncRNA inventory to fundamentally dissect the architecture of eukaryotic complexity. Over the ...

MicroRNAs in placental health and disease

Lin-4 does not encode a protein product but instead gives rise to a small RNA transcript of 22 nucleotides with complementarity to 3′-untranslated regions of ...

HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity ...

S4. Regulatory landscape associated with KDM3A target genes. (A) Western ... Preeclampsia is a multifaceted disease that can be associated with placental ...

Role of epigenetics and alterations in RNA metabolism in ...

Modulation in the epigenetics machinery including histone modifications, DNA methylation and non-coding RNAs dysregulation, could be crucial ...

Placental Microarray Profiling Reveals Common mRNA and lncRNA ...

In addition to immunological related pathways involved in IUGR, several studies have also highlighted the importance of gene dysregulation ...

Single nuclei RNA-seq of mouse placental labyrinth development

A time-course of single nuclei RNA-seq of the mouse placenta identifies trophoblast subtypes and the genes, signaling events, ...

Genome-wide landscape of RNA-binding protein target site ...

RBP dysregulation explains a substantial amount of heritability not captured by large-scale molecular quantitative trait loci studies and has a stronger impact ...

Dynamic landscape and regulation of RNA editing in mammals.

Related reading · Genetic effects on gene expression across human tissues · Hydrography shapes community composition and diversity ofamoA-containing ...

Dynamic landscape and regulation of RNA editing in mammals

Using the GTEx data and others, a comprehensive analysis of adenosine-to-inosine RNA editing in mammals is presented; targets of the various ADAR enzymes ...