Metabolic Reprogramming Supports IFN|γ Production by CD56 ...

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells

... support processes such as IFNγ production, and includes ... Metabolic reprogramming supports IFN-γ production by CD56 bright NK cells.

CD56 bright NK cells exhibit potent antitumor responses following IL ...

Metabolic reprogramming supports IFN-γ production by CD56bright NK cells. J Immunol. 2016;196(6):2552–2560. View this article via: PubMed ...

Tumor-treating fields increase cytotoxic degranulation of natural ...

27. Keating, S.E. ∙ Zaiatz-Bittencourt, V. ∙ Loftus, R.M. ... Metabolic Reprogramming Supports IFN-γ Production by CD56 bright NK Cells. J. Immunol. 2016 ...

Canonical TGF-β Signaling Pathway Represses Human NK Cell ...

C. M.. Gardiner . 2016 . Metabolic reprogramming supports IFN-γ production by CD56bright NK cells. J ...

CD56 bright NK cells are more metabolically active ... - ResearchGate

NK cell subsets that produce cytokines are metabolically... Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells. Article. Full-text ...

Human tissue-resident NK cells in the lung have a higher ... - PNAS

No significant metabolic differences were observed for CD56 ... Keating et al., Metabolic reprogramming supports IFN-γ production by CD56bright NK ...

Cytokine-induced natural killer cell training is dependent on cellular ...

4], and CD3 [clone 145-2C11]; humans: CD56 [clone REA196] and CD3 [clone REA613]). ... , et al. Metabolic reprogramming supports IFN-γ production ...

The Tumor Microenvironment—A Metabolic Obstacle to NK Cells ...

Furthermore, CD56bright NK cells, due to their higher metabolic activity, can produce more IFN-γ during an immune response. ... Metabolic Reprogramming Supports ...

Dysregulation of Metabolic Pathways in Circulating Natural Killer ...

This metabolic adaptation is necessary for CD56bright cells to produce large quantities of IFN-γ. ... , et al. Metabolic reprogramming supports ...

Metabolic regulation of NK cell function - Immunometabolism

... IFN-γ production by CD56 bright cells. In contrast ... Metabolic reprogramming supports IFN-gamma production by CD56bright NK cells.

Immunometabolism of T cells and NK cells: metabolic control of ...

Metabolic reprogramming supports IFN-γ production by CD56bright NK cells. J Immunol. 2016;196(6):2552–60. https://doi.org/10.4049/jimmunol ...

Increased lipid metabolism impairs NK cell function and mediates ...

... γ expression except CD56dimCD16− NK cells ... , et al. Metabolic reprogramming supports IFN-γ production by CD56bright NK cells.

Increased lipid metabolism impairs NK cell function ... - UQ eSpace

Metabolic Reprogramming Supports. 428. IFN-gamma Production by CD56bright NK Cells. J Immunol. 2016;196(6):2552-2560. 429. 15. Marcais A, Cherfils-Vicini J ...

Unlocking the potential of T‐cell metabolism reprogramming ...

Cytotoxic CD4+ T cells rely heavily on aerobic metabolic pathways to perform their core function in cytokine production. ... Improve IFN-γ ...

Metabolic programs drive function of therapeutic NK cells in hypoxic ...

... CD56bright immature cells, CD57+ ... Finlay, C. M. Gardiner, Metabolic reprogramming supports IFN-γ production by CD56bright NK cells.

Metabolic Reprograming via Deletion of CISH in Human iPSC ...

For example, interferon. (IFN)-g production via activating NK receptors requires glucose-driven oxidative phosphorylation (OxPhos) (Keppel et al., 2015).

Metabolic signatures of immune cells in chronic kidney disease

increases iNKT cell proliferation and IFN-γ production by pro- moting TCR recycling. ... Kelly B and OrNeill LA (2015) Metabolic reprogramming in ...

CD16 pre-ligation by defucosylated tumor-targeting mAb sensitizes ...

Experiments were performed on NK cell cultures which were more than 80% pure (CD3−CD56+). ... Metabolic reprogramming supports IFN-γ production by ...

ARID5B regulates metabolic programming in human adaptive NK cells

Adaptive CD3−CD56dimCD57+NKG2C+ NK cells exhibited metabolic hallmarks ... metabolism and IFN-γ production. Furthermore, we found that ARID5B directly ...

Abnormalities of quantities and functions of CD56bright natural killer ...

... CD56 bright NK cells to secrete IFN-γ. IL-18 is a newly ... Metabolic reprogramming supports IFN-γ production by CD56bright NK cells.