Novel insights into the genetic architecture of pregnancy glycemic ...

Identification of HKDC1 and BACE2 as Genes Influencing Glycemic ...

Defining the underlying genetic architecture of maternal glycemia during pregnancy may assist in future efforts to identify women at risk for ...

Development and validation of a multivariable genotype-informed ...

This study provides insight into genetic risk factors associated with the development of gestational diabetes mellitus within the Mexican population. We ...

Novel Insights Arising From the Definition of Genes for Monogenic ...

The identi- fication of the underlying molecular genetics opens the possibility for understanding the genetic architecture of clinically defined categories of ...

Insight into genetic, biological, and environmental determinants of ...

Regulatory differences in blood glucose and insulin levels are both heritable traits. When estimated separately, the single nucleotide polymorphism (SNP)-based ...

Genetics of Type 2 Diabetes—Pitfalls and Possibilities - MDPI

Many hypotheses have been proposed to define the genetic architecture of T2D: one hypothesis suggested that the unexplained heritability lies in a large number ...

Integrative cross tissue analysis of gene expression identifies novel ...

Among novel genes of interest are genes previously linked to related traits such as HKDC1 (pregnancy- ... provides insight into the genetic architecture of type 2 ...

Nicholas Mancuso, PhD - Keck School of Medicine of USC

Novel insight into the etiology of ... Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits Am J Hum Genet.

Trans-ancestry genome-wide association study of gestational ...

To gain novel insight into the genetic architecture of GDM, the GENetics of Diabetes In Pregnancy (GenDIP) Consortium assembled GWAS of ...

Identification and Potential Clinical Utility of Common Genetic ...

Our results indicate that the genetic architecture of glucose metabolism exhibits both similarities and differences between the pregnant and non ...

Finding Genetic Risk Factors of Gestational Diabetes

GDM is thought to have strong heritability. GDM women have an increased positive family history of T2DM. Compared to pregnant women with normal ...

The Genetic Architecture of Diabetes in Pregnancy - Thieme Connect

The genetic architecture of diabetes mellitus in general and in pregnancy is complex, owing to the multiple types of diabetes that comprise both complex/ ...

Genetics of Type 2 Diabetes - Karger Publishers

... novel genetic associations with continuous traits in the presence or ... insights into the genetic architecture and pathophysiology of type 2 diabetes.

Diabetes Mellitus and Pregnancy: An Insight into the Effects ... - MDPI

Epigenetic changes on DNA (left) or histones (right) in specific genes caused by diabetes during gestation. The scheme shows the type of epigenetic alteration ...

Publications – PGC - Psychiatric Genomics Consortium

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. ... Genetic Architecture and Identifies Novel Risk ...

World Journal of Diabetes - Baishideng Publishing Group

Metabolomic and genetic architecture of gestational diabetes ... Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese ...

GWAS Catalog - EMBL-EBI

... insights into the genetic architecture of type 2 diabetes. Ng MC et al. 2014 ... novel genetic and molecular risk factors for gestational diabetes and glycaemic ...

Maternal genome-wide association study identifies a fasting glucose ...

Our study demonstrates that maternal genetic variation at MTNR1B influences offspring birth weight and supports a broader role of genetic ...

panhong (0000-0003-4568-3119) - ORCID

Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities ... Contributors: Zhu, Huanhuan; Xiao, Han; Li, Linxuan; ...

OUCI

... genetic insights into the sex-dimorphism effects on ... Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities.

The role of genetics and epigenetics in the pathogenesis of ...

The results from an analysis of placental DNA methylation patterns of 1,030 pregnant women showed that women who develop GDM have higher levels ...