Off|Label Drug Use in Cancer Treatment

Using Off-Label Drugs for Cancer Prevention and Adjuvant Treatment

Cancer cells adapt to toxic environments (such as chemotherapy) and rapidly mutate to escape eradication. Prudent use of adjuvant “off-label” drugs can ...

Understanding Unapproved Use of Approved Drugs "Off Label" - FDA

You may be asking yourself why your healthcare provider would want to prescribe a drug to treat a disease or medical condition that the drug is ...

Off-Label Drug Use for Cancer Therapy and National Health Care ...

It further shows that most oncologists find that the Health Care Financing Administration and private insurance carriers are increasingly ...

What Do Cancer Patients Need to Know About "Off-Label" Drugs?

This additional use isn't on the official list of approved uses, hence the term "off-label." Why Would a Doctor Prescribe Off-Label? There are several ...

Off-label use of anticancer drugs - The Lancet Oncology

Most off-label prescription was reported in patients treated with palliative intent, some was associated with clinical benefits, and in specific cancers it ...

What is “Off-Label” Cancer Treatment and Does It Have Advantages?

Simply put, an off-label treatment would involve the use of a specific (FDA-approved) drug for a purpose other than the FDA designation.

Public Preference for Off-Label Use of Drugs for Cancer Treatment ...

This study aimed to quantify public preference for off-label cancer treatment outcomes, process, and costs, and perceived importance of associated adverse ...

Oncology (Cancer)/Hematologic Malignancies Approval Notifications

FDA does not issue approval announcements for every approval or drug label update that occurs in oncology and hematology. Please refer to Drugs@FDA for the ...

Off-label drug use in oncology: A systematic review of literature

Among adults, metastatic cancers and palliative care patients received the most off-label drugs. The off-label drug use unsupported by standard treatment ...

Off-Label Cancer Prescription: A Paradox to Evidence-Based Medicine

The use of surrogate endpoints in clinical trials has led to the approval then subsequent withdrawal of Avastin in metastatic HER2-negative ...

FDA Approved Drug Repurposing or Off-Label Use

Off-label uses that become standard-of-care treatments are listed in treatment guidelines by the National Comprehensive Cancer Network (NCCN). Patients might ...

Off-label Medication Use In Oncology - GlobalRPH

The usage of off-label drugs, including the compassionate use of investigational medications in cancer care, is widespread, but there is no ...

Going Off-Label | Cancer Today

A Cancer Treatment Staple ... Off-label use of drugs can be cutting-edge or routine. Studies suggest that historically, from 30 to 50 percent of ...

Title 24, §2320-F: Off-label use of prescription drugs for cancer

"Off-label use" means the prescription and use of drugs for medically accepted indications other than those stated in the labeling approved by the federal Food ...

Cancer Patients Could Benefit From “Off-label” Drugs

Some cancer patients may benefit from being treated with “off-label” drugs that are not routinely prescribed for their exact tumor type, ...

Making sense of off-label drug use - SingHealth Duke-NUS

In oncology, off-label uses mainly occur when the drug is used to treat unapproved clinical indications and line of treatment, or when the drug ...

Advancing perspectives on the off-label use of anticancer drugs

Larotrectinib has been approved as a monotherapy for patients with advanced colorectal cancer who are unsuitable for 5-Fu/leucovorin calcium.

Off‐label prescribing of targeted anticancer therapy at a large ...

Off-label drug prescribing is common in pediatric clinical medicine, though the extent and impact of this practice in pediatric oncology has ...

General Law - Part I, Title XXII, Chapter 175, Section 47K

''Off-label use'', a prescription drug used in the treatment of cancer which has been approved by the United States Food and Drug Administration and such drug ...

Medication Management: Off-Label Drug Use - Coverys

Unapproved uses can include indication, dosage, dosage form/route of administration, and duration of therapy. It is also considered off-label to use a drug in a ...