Oxidized LDL lipids increase β|amyloid production by SH|SY5Y ...

Cholesterol as a key player in amyloid β-mediated toxicity ... - Frontiers

The higher viscosity of lipid rafts is associated with increased β-secretase/APP interaction and higher Aβ production (Martín et al., 2010; Fabelo et al., 2014; ...

The relationship between blood lipids and plasma amyloid beta is ...

Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease. Clin Biochem. 2010;43:267–71 ...

Oxidized LDL lipids increase alpha-amyloid production by SH-SY5Y ...

Oxidized LDL lipids increase alpha-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. Home; Investigação ...

Circulating oxysterols in Alzheimer's disease: a systematic review ...

The key role of ApoE is to redistribute lipids through receptor-mediated uptake for neurite growth (Minagawa et al. ... oxidative stress and ...

Myeloperoxidase-generated reactive nitrogen species convert LDL ...

As with the protein markers of oxidation, production of lipid oxidation products was minimal in the absence of NO2–. ... oxidized low density lipoprotein ...

The Amyloid-β Pathway in Alzheimer's Disease | Molecular Psychiatry

ApoE4 expression increased, whereas ApoE3 reduced, Aβ ... The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid ...

Lipoprotein Lipase - Endocrinology and Metabolism

... low-density lipoprotein (LDL) cholesterol are produced as byproducts. LPL ... increasing the β-oxidation of fatty acids [56]. Six-week ...

Overfeeding Saturated Fat Increases LDL (Low-Density Lipoprotein ...

In line with these data, we show here that serum amyloid A in LDL was decreased after the UNSAT diet. Oxidation of circulating LDL particles ...

Low-density lipoproteins cause atherosclerotic cardiovascular ...

In addition, apoE, apoC-III, and serum amyloid A increase the affinity of LDL for arterial wall proteoglycans. ... Both native and oxidized forms ...

OxLDL plasma levels in patients with Alzheimer's disease - SciELO

... SH-SY5Y neuroblastoma ... Oxidized low density lipoprotein increases acetylcholinesterase activity correlating with reactive oxygen species production.

Oxidized Low-Density Lipoprotein Loading of Macrophages ...

Upon stimulation of TLR4, the rapid induction of IFN-β was inhibited in cells loaded with oxLDL, whereas the induction of other proinflammatory genes by TLR4 ( ...

Lipid peroxidation and Alzheimer's disease: Key role of Amyloid-β

Increased production of. Aβ in response to elevated oxidative stress has been documented in a number of in vitro studies, implying that production of monomeric ...

OxLDL as an Inducer of a Metabolic Shift in Cancer Cells

One of the most prominent features related to disturbed lipid metabolism is an increased production of oxidized low-density-lipoproteins (oxLDL), which results ...

Oxidized Low-Density Lipoprotein Stimulates Macrophage 18F-FDG ...

7 macrophages were stimulated with native LDL, oxLDL, or lipopolysaccharide. Cells were assessed for 18F-FDG uptake, lactate production, ...

1 LDL-Lipids from patients with hypercholesterolaemia and ... - CORE

(2014) Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation, Free Radical Biology and ...

Contribution of Dietary Intakes of Antioxidants to Homocysteine ...

... oxidized low density lipoprotein; folate; Vit A; β-carotene. Go ... increases LDL uptake in macrophages and atheroma production by lipids.

Oxidative Stress, Atherogenic Dyslipidemia, and Cardiovascular Risk

[14], virtually all traditional CVD risk factors are able to trigger ROS production or mediate the process of lipoprotein oxidation. Oxidized LDL (ox-LDL) ...

Cholesterol overload induces apoptosis in SH-SY5Y human ...

11. Do, H.T. ∙ Bruelle, C. ∙ Pham, D.D. ... Nerve growth factor (NGF) and pro-NGF increase low-density lipoprotein ... amyloid-beta production, aggregation, and ...

Baicalein protects against oxLDL-caused oxidative stress and ...

... increase AMPK phosphorylation (Figure 4B, 4C). Stimulations of endothelial cells with oxLDL caused phosphorylation of protein kinase C α and β ...

Oxidized LDL upregulates macrophage DPP4 expression via TLR4 ...

Oxidized low-density lipoprotein (oxLDL), but not native LDL, up-regulated DPP4 expression on macrophages with a preferential increase in CD36 + cells.