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Patient|Derived Head and Neck Cancer Organoids Recapitulate ...


Generation and Characterization of Patient-Derived Head and Neck ...

... Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids ... cancer PDO recapitulate the histology of the original tumors.

In Vitro Models of Head and Neck Cancer: From Primitive to Most ...

Most often, organoids for modeling HNSCC are obtained from resected tumor tissue of the patient. In the first stage, the biopsy sample is cleared of tissues of ...

Head and neck cancer organoids as a step towa | EurekAlert!

Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with ...

Patient-derived organoids to study and treat oral cancer - Search

This method allows patient-specific disease modeling of oral squamous cell carcinoma. These organoids have been used to accurately recapitulate ...

Genomic and single-cell characterization of patient-derived tumor ...

This study establishes patient-derived tumor organoids (PDOs) from 31 Head and Neck Squamous. Cell Carcinoma (HNSCC) patients, faithfully ...

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Additionally, the organoids recapitulated features associated with ... Patient-derived head and neck cancer organoids allow treatment ...

Clinicopathological Factors as Predictors for Establishment of ...

This study analyzed organoids derived from a prospective cohort of patients with cancers of the head and neck area in the University Medical ...

Pancreatic cancer organoids recapitulate disease and allow ... - PNAS

We describe a biobank of patient-derived pancreatic cancer organoids ... head and neck cancers. J. Biol. Chem. 282, 21477–21486 (2007). Crossref.

Clinical translation of patient-derived tumour organoids- bottlenecks ...

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening. ... Modern radiotherapy for head and neck cancer. Semin ...

The Benefits of PDX Models in Head and Neck Cancer Research

... patient-derived xenografts (PDX) in head and neck cancer research ... Organoids derived from head and neck cancer patient tumors recapitulate ...

Patient-derived cancer organoids for drug screening

Organoids from cancer patients, including head and neck cancer organoids ... Pancreatic cancer organoids recapitulate disease and allow ...

Correlation of the treatment sensitivity of patient-derived organoids ...

In this study, we aim to assess whether we can generate PDOs from head and neck squamous cell carcinoma (HNSCC) samples and whether PDOs can be used to predict ...

and Radiotherapy Screening Assay using Patient-Derived Organoids

This paper presents a method for medium-throughput drug screening using head and neck squamous cell carcinoma and colorectal adenocarcinoma ...

ORGAVADS: establishment of tumor organoids from head and ... - HAL

... head and neck squamous cell carcinoma ... Keywords Head and neck cancer, Patient‑derived tumor organoids, PARP inhibitors, Predictive functional ...

SU2C-Dutch Cancer Society Tumor Organoids Dream Team

The team established a panel of 23 head and neck squamous cell carcinoma (HNSCC)-derived organoid lines and observed differential responses to a panel of drugs ...

881P SOTO study - Annals of Oncology

... derived organoids (PDOs) with treatment outcomes in head and neck cancer patients ... The recapitulation of PDOs to that of the human samples will be ...

Correlation of the treatment sensitivity of patient-derived organoids ...

Correlation of the treatment sensitivity of patient-derived organoids with treatment outcomes in patients with head and neck cancer (SOTO): protocol for a ...

Tumor Organoids :: DKTK

Patient-derived tumor organoids (PDTOs) have recently emerged as preclinical tumor models. ... head and neck cancer). PDTOs have also been established for several ...

Technologies to Assess Drug Response and Heterogeneity in ...

Patient-derived cancer organoids (PDCOs) are organotypic 3D cultures grown from patient tumor samples. PDCOs provide an exciting opportunity ...

Correlation of the treatment sensitivity of patient- derived organoids ...

successful generated organoids from tissues in head and neck cancer patients. ... Recapitulates the Hypoxic Gradients and Cancer Stem. Cell ...