Patient|derived head and neck cancer organoids allow treatment ...

Clinicopathological Factors as Predictors for Establishment of ...

Patient derived organoids (PDOs) are 3D in vitro models and have shown to better reflect patient and tumor heterogeneity than conventional ...

Patient-Derived Cancer Organoids as Predictors of Treatment ...

Head-and-neck squamous cell carcinoma (HNSCC) organoids were developed and tested for treatment response towards standard-of-care chemotherapy ...

In Vitro Models of Head and Neck Cancer: From Primitive to Most ...

Increasing evidence indicates that organoids can predict response to treatment of the tumor from which they are derived [124]. In a pilot study, organoids ...

Predictive Potential of Head and Neck Squamous Cell Carcinoma ...

Second, the establishment of post-treatment tumor organoids may allow the identification of molecular mechanisms of tumor resistance. Depending ...

Patient-Derived Xenograft and Organoid Models for Precision ...

The identification and validation of strategies to individualise therapy of patients with head and neck squamous cell carcinoma require cellular and animal ...

Patient-derived cancer organoids to improve head and neck cancer ...

Patient-derived cancer organoids to improve head and neck cancer care · Research type · Full title · IRAS ID · Contact name · Contact email · Sponsor organisation.

Testing therapies on mini-tumors of head and neck cancer

Head and neck cancer is an aggressive type of cancer that often grows back, despite patients undergoing harsh treatments.

Testing therapies on mini-tumors of head and neck cancer

Researchers of the Hubrecht Institute (KNAW) and UMC Utrecht succeeded in growing mini-tumors (or organoids) of head and neck cancers, that can ...

Organoids as a tool in drug discovery and patient-specific therapy ...

Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer. Done AJ 1 ,. Birkeland AC 1. Author information ...

The applications and techniques of organoids in head and neck ...

Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity. · Medicine. Oral Oncology · 2018.

Harnessing Organoids to Tailor Treatments and Uncover New ...

... head and neck cancer treatment options by utilizing patient-derived organoids ... allowed us to evaluate the value of organoid technology ...

Patient-derived organoids to study and treat oral cancer - Search

Patient-derived organoids enable personalized oral cancer modeling and drug screening, enhancing treatment efficacy and research.

Correlation of the treatment sensitivity of patient-derived organoids ...

In this study, we aim to assess whether we can generate PDOs from head and neck squamous cell carcinoma (HNSCC) samples and whether PDOs can be ...

Organoids as a tool in drug discovery and patient-specific therapy ...

Patient- derived Head and Neck Cancer Organoids. Allow Treatment Stratification and Serve as a Platform for Biomarker Validation and Iden ...

Patient-Derived Head and Neck Cancer Organoids Allow Treatment ...

[Med] Organoids were established from head and neck cancer (HNC) patient tumor tissue and characterized using immunohistochemistry and DNA ...

Organoids Could Guide Personalized Therapy for Head and Neck ...

Since most head and neck cancer patients relapse, and there is strong evidence that subtypes exist, there is an urgent need for biomarkers ...

Genomic and single-cell characterization of patient-derived tumor ...

This study establishes patient-derived tumor organoids (PDOs) from 31 Head and Neck Squamous. Cell Carcinoma (HNSCC) patients, faithfully ...

Patient-derived organoids in cancer research and treatment - OUCI

Millen, Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification, Med, № 4, ...

New organoid biobank proves a useful tool for head and neck cancers

A new organoid biobank has demonstrated the ability to validate biomarkers, test personalized treatment strategies and study novel drugs for ...

Oral Mucosal Organoids as a Potential Platform for Personalized ...

Conditions for long-term culture of human mucosal organoids derived from head and neck squamous cell carcinoma (HNSCC) are described and responses to ...