REGEN|COV Antibody Combination and Outcomes in Outpatients ...

Effect of timing of casirivimab and imdevimab administration relative ...

The primary endpoint was vaccine-induced 50% inhibitory dilution neutralising antibody titres to SARS-CoV-2 spike protein, 56 days after the ...

REGEN-COV Antibody Cocktail in Outpatients with Covid-19

Results: Time-weighted average reduction in viral load (log10 copies/ml) through day 7 was significantly greater with REGEN-COV (combined 2400mg ...

The monoclonal antibody combination REGEN-COV protects ...

impact on either antibody or the REGEN-COV combination. ... REGEN-. COV Antibody Cocktail Clinical Outcomes Study in Covid-19 Outpatients.

REGEN-COV Antibody Cocktail Clinical Outcomes Study in Covid ...

The phase 3 portion of this adaptive, randomized, master protocol, included 4,057 Covid-19 outpatients with one or more risk factors for severe ...

REGEN-COV Antibody Combination in Outpatients With COVID-19

ABSTRACT BackgroundContinued SARS-CoV-2 infections and COVID-19-related hospitalizations highlight the need for effective anti-viral treatments in the ...

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Effectiveness of REGEN-COV combination monoclonal antibody ...

The secondary outcomes included National Institutes of Health-defined critical or severe COVID-19, preterm delivery, and perinatal outcomes.

REGEN-COV FDA Approval Status - Drugs.com

The clinical evidence from Regeneron's outpatient trial suggests that monoclonal antibodies such as casirivimab and imdevimab have the greatest ...

Regeneron EUA HCP Fact Sheet 01242022 - FDA

Monoclonal antibodies, such as REGEN-COV, may be associated with worse clinical outcomes ... in ambulatory patients with COVID-19. A flat dose-response ...

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with ...

REGN-COV2 is a cocktail made up of two noncompeting, neutralizing human IgG1 antibodies that target the receptor-binding domain of the SARS-CoV-2 spike protein, ...

Patient-Reported Outcomes in COVID-19 Treatment with ...

This study aimed to assess the effects of a monoclonal antibody (mAb) combination on symptoms, daily function, and overall health-related ...

Effectiveness of REGEN-COV Antibody Combination in Preventing ...

REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19. New England Journal of Medicine. 2021. . Verderese JP, Stepanova M ...

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with ...

... , Gary Herman, and George D. Yancopoulos. 2021. REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19. New England Journal of Medicine.

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with ...

Safety was assessed in all patients. RESULTS. Data from 275 patients are reported. The least-squares mean difference (combined. REGN-COV2 dose ...

REGEN-COV antibody cocktail shown to significantly lower SARS ...

They have developed a fully human monoclonal antibody combination of casirivimab and imdevimab (REGEN-COV) that is directed against the receptor ...

Determinants of passive antibody efficacy in SARS-CoV-2 infection

For the treatment of outpatients with COVID-19, we found a significant association between the dose administered and efficacy in preventing hospitalisation ( ...

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with ...

Notably, participants without detectable serum antibodies at baseline had a higher median SARS-CoV-2 RNA. ... Adverse effects were comparable ...

Effectiveness of REGEN-COV antibody combination to reduce risk of ...

In a large single system evaluation of pregnant patients meeting criteria for outpatient management of COVID-19, infusion of REGEN did not reduce risk for ...

Impact of Antibody Cocktail Therapy Combined with Casirivimab ...

These findings suggest that REGEN-COV therapy in outpatients with COVID-19 has the potential to improve patient outcomes and substantially reduce the health ...

REGEN‐COV antibody combination in patients with ...

Here, we present our clinical experience on the outcome of 15 hematological patients treated with REGEN-COV for SARS-CoV-2 infection. Most ...