Recent advances in the role of Yes‐associated protein in dermatosis

Yes-associated protein (YAP) induces a secretome phenotype and ...

YAP overexpression in about 30% of all cases defines liver cancer patients (hepatocellular carcinoma; HCC) with shorter survival and early ...

Deletion of Yes-Associated Protein (YAP) Specifically in Cardiac ...

Our recent study showed that YAP plays a novel integrative role in smooth muscle phenotypic modulation by inhibiting smooth muscle–specific gene ...

Yes‑associated protein expression is associated with poor ...

The Hippo signaling pathway plays a crucial role in cellular differentiation, proliferation, apoptosis and tumorigenesis (15). Previous studies ...

Emerging Perspectives of YAP/TAZ in Human Skin Epidermal and ...

Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are key downstream effectors of the Hippo ...

Yes-associated protein (YAP) mediates adaptive cardiac ...

Haploinsufficiency of YAP in CMs led to attenuated hypertrophy, but increased fibrosis and apoptosis, and decreased cardiac function during PO. These findings ...

Investigation of the Possible Role of the Hippo/YAP1 Pathway in ...

Several lines of evidence indicate that the Hippo/Yes-associated protein 1 (YAP1) pathways might play a role in the pathogenesis of asthma. To ...

Matrix Mechanotransduction via Yes-Associated Protein in Human ...

YAP is a transcriptional coactivator that associates with DNA via its interaction with TEA domain (TEAD) DNA-binding proteins to induce transcription of target ...

YAP1 - Wikipedia

YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes ...

Role of Yes-associated protein in cancer: An update

The present review will focus on the canonical pathways of YAP, and will provide details on the most recent findings regarding its regulation and role in ...

The Biology of YAP/TAZ: Hippo Signaling and Beyond

In addition to Scribble, other polarity proteins may impinge on YAP/TAZ function. The apical crumbs complex (CRB) contains the transmembrane protein Crumbs and ...

β-Catenin Sustains and Is Required for YES-associated Protein ...

However, the precise molecular mechanisms by which YAP induces cholangiocarcinoma development remain unclear. New Findings. YAP drives ...

Yes-Associated Protein May Hold Prognostic Value in Cutaneous ...

A retrospective study analyzing tissue assays from patients with cutaneous melanoma demonstrated the promise of yes-associated protein (YAP) ...

Atopic dermatitis (AD) is characterized by impaired skin barrier function and immune system dysfunction. The expression and role of Yes- ...

Yes-associated protein promotes the abnormal proliferation of ...

Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway · List of references · Publications ...

Citations to YAP/TAZ regulates sprouting angiogenesis and ... - JCI

Recent advances in the role of Yes‐associated protein in dermatosis. Jia X, He L, Yang Z, Skin Research and Technology, 2023 · Metformin accelerates bone ...

YAP1 Gene - GeneCards | YAP1 Protein | YAP1 Antibody

Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. The Journal of biological ...

Role of Yes-Associated Protein in Breast Cancer | Encyclopedia MDPI

The hippo/yes-associated protein (YAP) protein is a critical oncogenic mediator within the Hippo signaling pathway and has been implicated ...

Loss of Yes-associated Protein Represents an Aggressive Subtype ...

Background: Yes-associated protein (YAP) is a downstream effecter of Hippo signaling pathway, and has been linked to the initiation and development of ...

Expression characteristics of the yes-associated protein in - Medicine

YAP may participate in the occurrence and development of non-TNBC as a tumor suppressor gene; however, it may also be a carcinogenic factor in ...

YAP1 (Yes-associated Protein 1) - Pancreapedia

YAP1 is expressed throughout development, organogenesis, and postnatal growth and it is functionally important in many types of cells. Therefore ...