Role of the Yersinia pestis phospholipase D

Acquisition of yersinia murine toxin enabled Yersinia pestis ... - OUCI

Yersinia murine toxin (Ymt) is a phospholipase D encoded on a plasmid acquired by Yersinia pestis after its recent divergence from a Yersinia ...

[PDF] Role of the Yersinia pestis phospholipase D (Ymt) in the initial ...

Role of the Yersinia pestis phospholipase D (Ymt) in the initial aggregation step of biofilm formation in the flea. Clayton O. Jarrett, Jacqueline M. Leung ...

Yersinia Pestis (Pathogenesis) - microbewiki

pestis, while YopJ's role is debated[17]. YopH disrupts focal complexes and inhibits pro-inflammatory signaling to help Y. pestis avoid host phagocytosis and ...

Yersinia pestis - Wikipedia

Yersinia pestis is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both Yersinia enterocolitica and Yersinia ...

Yersinia pestis - Antimicrobe.org

Experimental infections in animals and cell cultures have elucidated roles of virulence factors, some of which have been incorporated into promising vaccines.

Early Divergent Strains of Yersinia pestis in Eurasia 5000 Years Ago

The bacteria Yersinia pestis is the etiological agent of plague and has caused human pandemics with millions of deaths in historic times.

Yersinia pestis Genes Required to Infect the Flea Vector of Plague

Y. pestis Ymt and Hms proteins have complementary but distinct roles. Ymt is required for survival in the midgut compartment, but not the proventriculus ...

Pathogenicity and virulence of Yersinia - Taylor & Francis Online

pestis utilizes multiple mechanisms for adhesion to epithelial cells that may play overlapping roles during infection. For example, Y. pestis adherence to ...

Yersinia pestis insecticidal-like toxin complex (Tc) family proteins

The murine toxin (ymt) gene, which encodes a phospholipase D, is required for survival of Y. pestis within the flea midgut [8]. However ...

Molecular and Genetic Mechanisms That Mediate Transmission of ...

The ability to cause plague in mammals represents only half of the life history of Yersinia pestis. It is also able to colonize and produce a transmissible ...

Genome sequence of Yersinia pestis, the causative agent of plague

pestis CO92 also revealed the presence of a range of genes predicted to encode previously unknown surface antigens, which might have a role in ...

Yersinia pestis and Plague: Some Knowns and Unknowns

Triggering the expression and secretion function of the T3SS is used to stimulate the in vivo signal that occurs when Y. pestis contacts host ...

Retracing the Evolutionary Path that Led to Flea-Borne ... - Cell Press

Yersinia pestis is an arthropod-borne bacterial pathogen that evolved recently from Yersinia pseudotuberculosis, an enteric pathogen ...

like phospholipase D of Pseudomonas aeruginosa sugges

For example, the classic murine toxin (Ymt) of Yersinia pestis has. PLD activity (Rudolph et al., 1999), and a PLD has been implicated in the virulence of ...

Yersinia pestis and plague: an updated view on evolution, virulence ...

A complex set of virulence determinants, including the Yersinia outer-membrane proteins (Yops), the broad-range protease Pla, pathogen- ...

Acquisition of yersinia murine toxin enabled Yersinia pestis to ...

One key gene acquired during transition to the flea-borne life cycle encodes Yersinia murine toxin (Ymt), a phospholipase D enzyme that has an important role in ...

Yersinia pestis kills Caenorhabditis elegans by a biofilm ...

Using Y. pestis KIM5, which lacks the genes that are required for biofilm formation, we show that Y. pestis can kill C. elegans by a biofilm‐independent ...

Role of Early-Phase Transmission in the Spread of Yersinia pestis

In his discussion of the evolution of flea-borne transmission in Y. pestis, Hinnebusch (2005) emphasized the importance of two Y. pestis ...

Recent Findings Regarding Maintenance of Enzootic Variants of ...

Despite the widespread presence of bubonic plague in sylvatic reservoirs throughout the world, the causative agent (Yersinia pestis) evolved ...

Comparative Proteomic Studies of Yersinia pestis Strains ... - Frontiers

Yersinia pestis, the causative agent of plague, is a highly virulent bacterium responsible for millions of human deaths throughout history.