The Role of the Neural Exposome as a Novel Strategy to Identify ...

A Brief Introduction to the Exposome and Human Health

This article aims to reinforce the importance of exposomics via the idea, a fundamental tenet of biology, that human phenotype results from an ...

Multi-omics signatures of the human early life exposome

Environmental exposures during early life play a critical role in life-course health, yet the molecular phenotypes underlying environmental ...

The Relationship between Exposome and Microbiome - MDPI

Whereas both the exposome [1] and the microbiome have been studied separately as means of identifying novel sources of disease risk and discerning mechanisms, ...

The Human Exposome Map - Robert O. Wright, MD, MPH - YouTube

This presentation took place at the eighth exposome symposium organized by the Mount Sinai Institute for Climate Change, ...

The Exposome: A New Frontier in Disease Research | Metabolon

The human exposome encompasses all of the environmental exposures that an individual will encounter throughout their lifetime.

Center of Excellence For Translational Neuroscience and ...

... novel and improved therapeutic tools and strategies. ... David Jett, Program Director, Office of Neural Exposome & Toxicology, Division of Translational Research, ...

Questionnaire-based exposome-wide association studies for ...

The exposome interacts with individual genetic and epigenetic characteristics to affect human health and disease, but large-scale studies that ...

Adopting Mechanistic Molecular Biology Approaches in Exposome ...

In this regard, AOPs provide a useful framework, as they allow the identification of relevant exposure biomarkers using NAMs relevant to human ...

Articles | Molecular Neurobiology - SpringerLink

The Role of the Neural Exposome as a Novel Strategy to Identify and Mitigate Health Inequities in Alzheimer's Disease and Related Dementias. Ravid Granov ...

The importance of the exposome and allostatic load in the planetary ...

It is our contention that an “exposome perspective” will help break down silos and incorporate the ongoing work of physiological anthropology ...

An exposome connectivity paradigm for the mechanistic assessment ...

Metabolomics deals with the analysis of all the small molecules delivered by the homeostatic function; thus, they are found in cells, tissues, and biological ...

Mapping the Human Exposome - Science Philanthropy Alliance

The equivalent for mapping the exposome is an approach that identifies the environmental mediators that have the greatest effect on human biology and looks for ...

Differential neural circuitry behind autism subtypes with imbalanced ...

Applying this model to resting state fMRI data from the EU-AIMS LEAP dataset (n=509), we find that while the phenotypic subtypes share many ...

environmental health perspectives

The Importance of the Biological Impact of Exposure to the Concept ... receives royalties from his book The Exposome: A. Primer. G.W.M. and ...

A call for a Human Exposome Project | ALTEX

Exposomics is increasingly complemented by exposure science and biomonitoring to measure exposure, mechanistic understanding, human-relevant ...

Shedding light on the etiology of neurodegenerative diseases and ...

The combination of all environmental exposures, including pollutants, lifestyle factors and behaviors, over the lifespan is defined as “exposome ...

Role of the Exposome in Neurodegenerative Disease: Recent ...

A focus on the neural exposome. Neuron. 2022; 110: 1286–1289 ... Genome-wide analyses identify KIF5A as a novel ALS gene. Neuron ...

environmental exposures and autoimmune diseases

EXIMIOUS aims to deliver a novel approach to evaluating the human exposome – the cumulative exposure to various environmental factors over a ...

Progress in Characterizing the Human Exposome: a Key Step for ...

The objective of this contribution is to raise awareness within the health informatics community about the importance of dealing with data ...

The Exposome | ALS Center of Excellence - Research

The exposome refers to the full spectrum of environmental exposures that an individual encounters throughout their life, including everything from pollutants in ...