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The potential of proliferative and apoptotic parameters in clinical ...


Cancer and apoptosis: The apoptotic activity of plant and marine ...

The various genetic regulators of cell proliferation hold a remarkable role in cancer cell division and growth (as shown in Figure 2). The cell cycle plays a ...

Cell Proliferation Services - PeploBio

A programmed cell death process crucial for maintaining immune homeostasis. Apoptosis is evaluated through parameters such as phosphatidylserine exposure, ...

Prognostic Significance of Apoptosis in Synovial Sarcoma

The degree of apoptosis was analyzed in relation to several clinicopathologic parameters, cell proliferative activity, and immunohistochemical expression of ...

Circadian regulator BMAL1::CLOCK promotes cell proliferation in ...

... parameters. However, the underlying ... While these agents have the potential to improve patient ... proliferation and caused apoptosis in HCC cells ...

RB1 dual role in proliferation and apoptosis: Cell fate control and ...

Moreover we describe clinical studies exploring the possible utility of. RB1 as a predictive marker of response to both cytotoxic and cytostatic treatments ...

Augmentation of anti-proliferative, pro-apoptotic and oxidant profiles ...

Annexin V staining indicated augmented early and late apoptosis. PCT-ZN NSs pro-apoptotic activity was confirmed by the observed significant increased mRNA ...

Using flow cytometry to follow the apoptotic cascade

It also has been used to quantify the number of apoptotic cells in a culture and, more recently, in clinical samples. In this review, which updates an earlier, ...

Gramicidin inhibits human gastric cancer cell proliferation, cell cycle ...

Meanwhile, the migratory capacity and G2/M cell cycle were inhibited upon gramicidin treatment with significant cell apoptosis. Furthermore, our results showed ...

[Prognostic value of apoptotic and proliferative indices in solid tumors].

Given this, measurement of parameters of the apoptotic cell death and proliferative activity of tumor cells may be of great prognostic worth. The review present ...

Apoptosis, DNA Damage and Cell Proliferation Kit - BD Biosciences

(3) If staining for total DNA content is not desired, then the DAPI staining step can be omitted and fluorescent data for another parameter can then be measured ...

Cell Proliferation and Death | The Basic Science of Oncology, 6e

8.4.3 The Death Receptor Apoptotic Pathway ... Chapter 13 discusses the properties of tumor stem cells with high proliferative potential. ... When cells cease ...

Curcumin Has Anti-Proliferative and Pro-Apoptotic Effects on ...

The proliferation and migration of TC cells were evaluated with CCK-8 assay and scratch wound healing assay, respectively. Cell apoptosis was ...

Deregulation of apoptosis in acute myeloid leukemia - Haematologica

Apoptosis, or programmed cell death, is central to the development and homeostasis of the hematopoietic system. Dysregulation of apoptosis ...

PI3K/mTORC1/2 inhibitor PQR309 inhibits proliferation and induces ...

The present study revealed for the first time that this small molecule has a great clinical significance on GBM, and is a potential new anti- ...

Anti-proliferative and apoptosis induction activities of curcumin on ...

Cell viability was calculated on the basis of the equation: absorbance of the treated sample/absorbance of the control cells×100. All values are means of ...

Overview of Cell Viability and Survival | Cell Signaling Technology

Thus, cell proliferation assays are a useful tool for assessing cell viability or cell survival by providing a readout on the number of actively dividing cells ...

Pro-apoptotic and pro-proliferation functions of the JNK pathway of ...

The continuous appearance of cells in apoptosis causes persistent proliferative signalling that stimulates mitogenic activity of tumour cells.

Potential Treatment Options for Neuroblastoma with Polyphenols ...

Elevated Bax/Bcl-2 ratio, increased PARP cleavage, loss of MMP and cytochrome C release, and ROS generation all contribute to apoptotic cell death. Specific ...

Statins inhibit proliferation and induce apoptosis in triple-negative ...

Of potential clinical significance, we found significantly lower IC50 values for both statins in TNBC versus non-TNBC cell lines ...

378a-3p Restrains the Proliferation of Retinoblastoma Cells but ...

(E, F) Cell cycle distribution and apoptosis assessed by flow cytometry. Statistical values were measurement data and expressed as mean ± standard deviation.