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Therapeutic targeting of the tumor microenvironment


Targeting Tumor and Tumor Microenvironment Vulnerabilities

Authors posit that mitochondria-targeted drugs combined with standard-of-care chemotherapy, radiation therapy, and immunotherapy are likely ...

Chapter - Manipulating the Tumor Microenvironment - Eurekaselect

The focus of treatment approaches has largely been on eliminating tumor cells. However, recent studies have shown that there is cross talk between tumor cells ...

Therapeutic targeting of the tumor microenvironment - CORE

The supporting players in the tumor microenvironment include stromal fibroblasts, infiltrating immune cells, the blood and lymphatic vascular networks, and the ...

Therapeutic targeting of the tumor microenvironment

Therapeutic targeting of the tumor microenvironment ... ; Therapeutic targeting of the tumor microenvironment. ; Joyce, Johanna A. ;. ; Cancer cell ...

Therapeutic targeting of tumor-associated macrophages through ...

Background: The tumor microenvironment (TME) plays integral roles in prostate cancer progression and is a high value therapeutic target.

Targeting the Tumor Microenvironment for Improving Therapeutic ...

This paper reviews recent advances in the improvement of therapeutic efficacy on the immune context of the TME and highlights its contribution to cancer ...

Advances in Therapeutic Targeting of Cancer Stem Cells within the ...

Despite great strides being achieved in improving cancer patients' outcomes through better therapies and combinatorial treatment, several ...

Therapeutic targeting of the tumor microenvironment - OUCI

Achen, Focus on lymphangiogenesis in tumor metastasis, Cancer Cell, № 7, с. · Allinen, Molecular characterization of the tumor microenvironment in breast cancer, ...

Therapeutic targeting of tumor-associated myeloid cells ... - PNAS

Tumor-associated myeloid cells (TAMCs) are key drivers of immunosuppression in the tumor microenvironment, which profoundly impedes the clinical ...

Targeting the Tumor Microenvironment - AACR Journals

Cancer therapy has evolved beyond solely targeting cancer cells and now considers the tumor microenvironment (TME) as well. The cellular and acellular ...

A Comprehensive Exploration of Agents Targeting Tumor ...

The tumor microenvironment (TME) encompasses the complex and diverse surroundings in which tumors arise. Emerging insights highlight the ...

Strategies for cancer therapy: targeting tumor microenvironment and...

Targeting TME components may be effective in improving tumor therapy. Using nanotechnology for drug delivery is of great interest.

About the Special Issue - Exploration of Targeted Anti-tumor Therapy

With an increasing incidence over time, there is a great need for effective therapies with minimal side effects. The role of the tumor microenvironment (TME) in ...

Antitumor Therapy Targeting the Tumor Microenvironment

ECM components have a profound influence on the tumor growth, progression, invasion, and metastasis, indicating them as attractive anticancer ...

Imaging and therapeutic targeting of the tumor immune ...

The important role of tumor microenvironmental elements in determining tumor progression and metastasis has been firmly established.

Effective Targeting of the Tumor Microenvironment for Cancer Therapy

Prospective analysis of HA content was used to predict response to PEGPH20 of squamous cell-type explants from patients with non-small cell lung cancer in nude ...

Therapeutic targeting of the tumor microenvironment - CORE

The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment · Resveratrol and ...

Updates on the hematologic tumor microenvironment and its ...

Updates on the hematologic tumor microenvironment and its therapeutic targeting · A maladapted vascular niche induces the generation and ...

Targeting the tumor microenvironment in cholangiocarcinoma

This intricate microenvironment has multiple immunosuppressive elements that promote tumor cell survival and therapeutic resistance. Accordingly, there is a ...

Therapeutic targeting of the tumor microenvironment - Revvity

Thus, tumour cell function is critically dependent on the local microenvironment; something which needs to be considered when devising therapeutic strategies to ...