Tumor|Host Interactions and Systemic Effects of Neoplasms

Tumor Biology and Microenvironment Research - NCI

Understanding the cellular, molecular, and biochemical interactions of tumors within their microenvironment is essential to improving cancer ...

Mechanisms of regulatory T cell infiltration in tumors

Introduction. The interaction between tumor cells and immune cells plays an important role in tumor development and progression. · Characteristics and phenotypes ...

The Initial Hours of Metastasis: The Importance of Cooperative Host ...

Temporal dynamics of host–tumor cell interactions during the early steps of the metastatic cascade. Tumor cells intravasate, rapidly transit through the ...

Tumour–host interactions through the lens of Drosophila

A hallmark still awaiting recognition is cancer's ability to induce systemic shifts of patient physiology. Such effects, in which the tumour can ...

Cancer - Tumor Effects, Symptoms, Treatment | Britannica

Cancer - Tumor Effects, Symptoms, Treatment: The signs and symptoms of benign or malignant tumours result for the most part from the local ...

Brain Tumors - AANS

The wafers slowly secrete the drug into the tumor, and the patient receives chemotherapy with the systemic side effects of treatment. Laser Interstitial ...

Systemic Regulation of Cancer Development by Neuro-Endocrine ...

The overarching view of current tumor therapies simplifies cancer to a cell-biology problem in which neoplasms are caused solely by ...

Tumor Rejection by Disturbing Tumor Stroma Cell Interactions

The stroma of solid tumors is a complex network of different cell types. We analyzed stroma cell interactions in two tumor models during cyclophosphamide (Cy)- ...

The tumor microenvironment and its contribution to tumor evolution ...

Carcinoma-associated fibroblasts, leukocytes, bone marrow-derived cells, blood and lymphatic vascular endothelial cells present within the tumor ...

Targeting Tumor Stroma - Oncology & Cancer Treatment

For example, the existence of certain cancer-associated fibroblasts (CAFs), a major type of stromal cell in tumors, can be predictive of cancer recurrence after ...

Immune surveillance of tumors - JCI

The idea that the immune system, which so effectively protects the host from microbial pathogens, might also recognize and destroy tumor cells ...

Not only tumor but also therapy heterogeneity - Annals of Oncology

∙ Nagy, J.A. ∙ Dvorak, A.M.. Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies. Cancer Cells. 1991; 3:77-85.

Hallmarks of cancer: Interactions with the tumor stroma

Additional complexity is brought about by diverse effects on pericyte recruitment depending on the cellular source of PDGF-B. Tumors grown in ...

Sepsis and Cancer: An Interplay of Friends and Foes - ATS Journals

Animal models have suggested that local malignant tumors can promote systemic immune alterations associated with increased susceptibility to ...

Role of tumor microenvironment in cancer progression and ...

When tumor cells form pro-tumorigenic cocoons, reprogramming occurs in the tumors and their constituent cells to exploit the interaction with ...

Heart Tumor Symptoms, Types & Treatment | Columbia Surgery

Treatment options are dependent upon several factors including type of tumor, tumor size and location, presence or absence of systemic metastases and the ...

Hallmarks of Cancer: New Dimensions - AACR Journals

One common characteristic of tumors (or regions within tumors) is hypoxia, consequent to insufficient vascularization. Hypoxia, for example, ...

Tumor-associated neutrophils and macrophages interaction ...

Those results suggested that the effects of TANs and TAMs interaction on ICC tumor progression rely on STAT3 signaling. ... The tumour-induced systemic ...

Cancer Glossary | Definitions & Phonetic Pronunciations

carcinoid tumor [car-sin-oyd]. Tumors that develop from neuroendocrine (nerve and endocrine) cells. They can release certain hormones which can cause symptoms ...

Tumor-associated macrophages: an accomplice in solid tumor ...

Much noticeable evidence shows that the tumor microenvironment (TME) engage in cancer initiation and promotion of tumor growth [1]. TME comprise ...