Tumour necrosis factor

Tumor necrosis factor superfamily - Wikipedia

Tumor necrosis factor superfamily ... The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF ...

Historical perspectives on tumor necrosis factor and its superfamily

The tumor necrosis factor (TNF) superfamily, composed of 19 ligands and 29 receptors, plays highly diversified roles in the body.

Tumor necrosis factor Definition & Meaning - Merriam-Webster

The meaning of TUMOR NECROSIS FACTOR is a protein that is produced chiefly by monocytes and macrophages in response especially to endotoxins ...

Tumor Necrosis Factor Receptor-Associated Periodic Syndrome

TRAPS is a rare multisystem genetic disorder characterized by unexplained periodic episodes of fever associated with additional symptoms including muscle pain ...

Information on Tumor Necrosis Factor (TNF) Blockers - FDA

Information on Tumor Necrosis Factor (TNF) Blockers (marketed as Remicade, Enbrel, Humira, Cimzia, and Simponi)

Tumor Necrosis Factor Alpha Signaling and Organogenesis - Frontiers

TNF-α plays important roles in various biological processes, such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and ...

Tumor Necrosis Factor-α human - Sigma-Aldrich

Tumor Necrosis Factor-α human (TNF-α); TNF-α, HEK 293 cells, cell culture; Suitable for mammalian cell culture; The TNFα (tumor necrosis factor α) gene is ...

tumour necrosis factor shed form | Ligand page

GtoPdb Ligand ID: 5074 · Abbreviated name: TNF shed form · Synonyms: cachectin | necrosin | TNF alpha soluble form | tumor necrosis factor soluble form.

Entry - *191160 - TUMOR NECROSIS FACTOR; TNF - OMIM

Online Mendelian Inheritance in Man (OMIM) is a comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and ...

Tumor necrosis factor | German Center for Infection Research

Tumor necrosis factor (TNF) is an important cell signaling factor of the immune system. It is involved in acute inflammatory reactions towards gram-negative ...

Tumor necrosis factor receptor-associated periodic syndrome

Tumor necrosis factor receptor-associated periodic syndrome (commonly known as TRAPS) is a condition characterized by recurrent episodes of ...

Anti-tumour Necrosis Factor Alpha (anti-TNF-alpha) - Patient.info

The cytokine inhibitors affecting TNF-alpha currently licensed in the UK are adalimumab, certolizumab pegol, etanercept, golimumab, and infliximab.

Tumor necrosis factor | DrugBank Online

Functions: cytokine activity / identical protein binding / protease binding / tumor necrosis factor receptor binding

Tumour necrosis factor and cancer - Pathological Society - Wiley

TNF can activate cancer cell survival and proliferation pathways, trigger inflammatory cell infiltration of tumours and promote angiogenesis and tumour cell ...

Tumor Necrosis Factor (TNF) - Science

CARSWELL, E.A., ENDOTOXIN-INDUCED SERUM FACTOR THAT CAUSES NECROSIS OF TUMORS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED ...

Tumour necrosis factor-α as a tumour promoter

2 Tumour necrosis factor-α (TNF-α). TNF-α is a key cytokine involved in inflammation, immunity and cellular organisation.

1TNF: THE STRUCTURE OF TUMOR NECROSIS FACTOR-ALPHA ...

The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. Eck, M.J., Sprang, S.R. ... PubMed Abstract: The three- ...

The role of tumour necrosis factor-α and tumour ... - Oxford Academic

TNF-α induces DNA damage to multiple cell types. In order to determine sufficiency of a cytokine in inducing systemic DNA damage in vivo, 500 ng ...

Tumour necrosis factor alpha (IPR002959) - InterPro entry - EMBL-EBI

Tumor necrosis factor (TNF) (also known as TNF-alpha or cachectin) is a monocyte-derived cytotoxin that has been implicated in tumour regression, septic shock ...

Tumor Necrosis Factor (TNF) Inhibitors: A Clinical Primer - MedCentral

TNF inhibitors are relative newcomers to pain management and include Remicade (infliximab) and Enbrel (etanercept), Humira (adalimumab), Cimzia (certolizumab ...