X‐ray crystallography at macromolecular resolution

Advances and challenges in time-resolved macromolecular ...

Mature structural analysis tools of macromolecular crystallography can then be adapted to allow x-ray diffraction data to be analyzed in terms ...

Time-Resolved Macromolecular Crystallography at Modern X-Ray ...

Time-resolved macromolecular crystallography unifies protein structure determination with chemical kinetics. With the advent of fourth ...

Time-Resolved Macromolecular Crystallography at Pulsed X-ray ...

The focus of structural biology is shifting from the determination of static structures to the investigation of dynamical aspects of macromolecular function ...

Macromolecular X-Ray Crystallography Facility Archives

The X-ray Crystallography Facility has invested in different chromatography columns to facilitate the purification of proteins and peptides using size-exclusion ...

Macromolecular X-ray crystallography - CNB-CSIC

Protein X-ray crystallography is a high-resolution technique that allows us to study protein structure at atomic level.

Experimental phasing opportunities for macromolecular ... - Nature

This method has the added advantage of choosing the crystal size, as smaller crystals absorb less X-rays at longer wavelengths. Crystals of ...

Comparison of X-ray Crystallography and NMR Spectroscopy

In macromolecular structure determination, NMR and protein crystallography can be complementary techniques [150, 151], and NMR-resolved macromolecular (ligand- ...

Macromolecular room temperature crystallography | Cambridge Core

X-ray crystallography enables detailed structural studies of proteins to understand and modulate their function. Conducting crystallographic ...

(IUCr) On the feasibility of time-resolved X-ray powder diffraction of ...

However, because of their low flux, such sources are not commonly used to study the structural dynamics of macromolecules. This article examines ...

Emerging Time-Resolved X-Ray Diffraction Approaches for Protein ...

Proteins guide the flows of information, energy, and matter that make life possible by accelerating transport and chemical reactions, ...

Macromolecular X-Ray Diffraction Facility - University of Birmingham

X-ray diffraction is unsurpassed in its ability to provide atomic-resolution images of macromolecules of virtually any size, furnishing us with detailed ...

The design of macromolecular crystallography diffraction experiments

The measurement of X-ray diffraction data from macromolecular crystals for the purpose of structure determination is the convergence of two processes: the ...

Macromolecular X-ray Crystallography Core (RRID:SCR_019310)

The Macromolecular X-Ray Crystallography Lab in the Department of Biochemistry provides resources for crystallization and structure determination of biological ...

Macromolecular Structure Determination by X-ray Crystallography

X-ray diffraction is a well-established method to elucidate the atomic structure of single- crystal macromolecules. An image of the macromolecule forming ...

Macromolecular X-ray Crystallography Facility

X-ray crystallography is most widely used to determine the three dimensional structure of proteins, nucleic acids, and large nucleoprotein complexes. It ...

Full article: Machine learning applications in macromolecular X-ray ...

In X-ray crystallography, and its application to structural biology, machine learning is finding a home within expert and automated systems, is forecasting ...

MX: Macromolecular Crystallography - Diamond Light Source

Macromolecules tend to form small, imperfect and weakly diffracting crystals. The high brightness of synchrotron X-rays makes the collection of precise ...

Macromolecular Structure Determination by X-ray Crystallography

Abstract. For more than 50 years, single‐crystal X‐ray diffraction has remained at the forefront of structural studies of biological macromolecules and complex ...

X-Ray Diffraction by Macromolecules - SpringerLink

X-Ray Diffraction by Macromolecules comprises three parts: fundamental, experimental and analytical, and the volume as a whole may serve as an intermediate ...

X-ray macromolecular crystallography: an overview - Moodle@Units

Visualising a 3D electron density map over the entire unit cell can be daunting. To visualise electron density maps we use high resolution interactive graphics,.