histopathological and genetic study on the protective role of Î² ...

Articles in Press - The American Journal of Pathology

A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury. Samuel Mon-Wei Yu,; Emily King,; Miguel ...

Unsupervised identification of disease states from high‐dimensional ...

This table summarizes the analysis of physiology (Fig 2B), histology ... Overall, our analysis of tolerance confirms the expected role of ...

An inducible genetic tool to track and manipulate specific microglial ...

Recent single-cell RNA sequencing studies have revealed distinct microglial states in development and disease. These include proliferative-region-associated ...

Identification of histopathological classification and establishment of ...

These genes were intersected with 19 immune-related genes obtained by pathological features analysis, and one up-regulated gene BMP3 and one ...

Sharma Lab - La Jolla Institute for Immunology

... genes function in relation to a given biological system of interest. ... Molecular Mechanisms Underlying Novel Interferonopathies. In addition to their protective ...

Large sequencing effort links new genes to Crohn's disease risk

The findings help illuminate key cells and biological pathways involved in the disease, which could help inform the development of future ...

Genetic Evidence for a Protective Role for Heat Shock Factor 1 and ...

shows the results of histological analysis of colonic tissues prepared from DSS-administered and untreated HSF1-null and wild-type mice. More exten- sive ...

Protective and Harmful ER Stress Responses in Pancreatic β-Cells

JNK target JunB may also play a role in lipotoxic cell death. Active JNK phosphorylates JunB, leading to its degradation in the proteasome. JunB ...

NGF (−198C > T, Ala35Val) and p75 NTR (Ser205Leu) gene ...

In the present study, we evaluated the impact of SNPs in these genes on the maintenance of liver function at different stages of inflammation ...

A Protein-Truncating HSD17B13 Variant and Protection from ...

... genetic variants and chronic liver disease and the histopathological severity of liver disease. Methods. Study Design and Participants. We ...

Genetics of Colorectal Cancer (PDQ®) - NCI

... histology, specific gene-directed testing can be ... bParticipants were invited to complete questionnaires before clinical genetic testing ...

Digital Commons @ University of South Florida

2017. Genetic and Histological Alterations Reveal Key Role of. Prostaglandin Synthase and Cyclooxygenase 1 and 2 in Traumatic. Brain Injury–Induced ...

The role of complement in kidney disease: conclusions from a ...

The studies enroll adults only unless specified. b ... Opinions and preferences regarding genetic screening and testing are highly variable among patients.

Dissecting the Shared Genetic Architecture of Suicide Attempt ...

Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained ...

Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE ...

8 B–D), demonstrating the remarkable sensitivity of outer retinal cells to apoptosis in the presence of oxidative stress. Apoptosis in explants ...

5191. Occupational Exposure to Hazardous Chemicals in ...

Commercially prepared kits such as those used in performing pregnancy tests in which all of the reagents needed to conduct the test are contained in the kit. (b) ...

Genetic disruption of cyclooxygenase‐2 does not improve ...

Increasing evidence suggests a role for cyclooxygenase‐2 (COX‐2) in traumatic brain injury (TBI). In the present study, the role of COX‐2 in ...

Natural single-nucleotide deletion in chymotrypsinogen C gene ...

studies, the observations provide conclusive evidence for the protective role of CTRC against pancreatitis. Research · Gastroenterology · Inflammation · Find ...

Deciphering the Role of Host Genetics in Susceptibility to Severe ...

... protective role in COVID-19 pathogenesis needs further study. Within ... The latter study instead identified an association between the HLA-B*0703 and ...

Genetic and histopathological alterations induced by cypermethrin ...

... Protective role of sesame oil. Journal of Environmental Science and Health Part B 47: 306–314. Crossref · PubMed · Google Scholar. 9. Saxena P, Saxena AK (2010) ...