A method of respiratory phase optimization for better dose sparing of ...

Motion management of lung tumors: A retrospective analysis...

Volumes of all OARs were comparable except the lung. OAR doses were almost same in both phases. Significantly higher normal lung volume was found in the EI ...

Dosimetric Impact of Respiratory Motion During Breast Intensity ...

Breast IMRT allows for the radiation dose to conform more precisely to the breast tissue while limiting the irradiation of normal tissue. Moreover, a more ...

Evaluation of respiratory gating – dose sparing and set-up

... best way to reduce random set-up deviation is by improving immobilization ... dose distribution should be expected between the different respiratory phases due to ...

Impact of Active Breathing Control-Deep Inspiration Breath Hold ...

Figure 2 Overview of respiratory phase CT images. (A) First DIBH CT scan: 3D-CT images were obtained with the ABC system, (B) second deep-breathing CT scan: 4D ...

Patient individual phase gating for stereotactic radiation therapy of ...

A treatment plan was calculated on a reference phase CT (rCT) and the dose for each breathing phase was calculated and accumulated on the rCT.

Fang-Fang Yin | Scholars@Duke profile: Publications

... dose delivered during each respiratory phase. The dose-per-phase is ... Phase Window and Frame Rate Optimization for On-board 4D Imaging Dose Reduction.

Absolute dose measurements for lung gated delivery stereotactic ...

Kang, A method of respiratory phase optimization for better dose sparing of organs at risks : a validation study in patients with lung cancer, Oncotarget, № 9, ...

Optimization strategies for respiratory motion management in ...

The dose is applied in only a few fractions and respiratory organ and tumor motion is a source of uncertainty additional to interfractional set- ...

API Sparing Techniques for Inhalation Toxicology Studies | IITRI

the intended dose compared to the more common oral or IV routes. The fraction of inhaled dose that is deposited in the lungs is affected by the aerodynamic ...

Impact of respiratory motion in dosimetric and clinical advantages for ...

The DIBH technique is a feasible tool to provide dosimetric and clinical advantages for adjuvant left-sided breast radiotherapy.

Lung Recruitment Maneuver - Physiopedia

In prone position due to the asymmetry of lungs with more lungs field available in the dorsal part, recruiting more alveoli and thus increase ventilation.

Treatment plan optimization incorporating respiratory motion

displacement vector fields at different breathing phases, a set of deformed beamlets is obtained by mapping the dose to the primary phase. Optimization ...

Protective antibodies elicited by SARS-CoV-2 spike protein ...

NHPs were challenged intranasally and intratracheally with a high dose (3 × 106 plaque forming units) of SARS-CoV-2 (USA-WA1/2020 isolate). Two days after ...

Pulmonary delivery of ISCOMATRIX influenza vaccine induces both ...

The 375-fold reduction in antigen dose and improved mucosal antibody responses, compared to the current vaccine, suggests that mucosal delivery ...

The Management of Respiratory Motion in Radiation Oncology - AAPM

... increased dose to the tumor while sparing healthy tissue will improve the balance between complications and cure. Methods that explicitly account for ...

Immunogenicity and Protective Efficacy of Dose-Sparing Epigraph ...

... respiratory tract [2,3]. IAV in swine (IAV-S) is often characterized by a ... In contrast, pigs immunized with the low-dose Epigraph demonstrated more ...

Advanced Development of New Influenza Vaccines

Goal #1: Establish and maintain a dynamic pre-pandemic influenza vaccine stockpile ava a e. M. (2 d. /. ) il bl for 20 M persons (2 doses/person) or more ...

Phase 1, randomized, rater and participant blinded placebo ...

timepoints more than 1 month post dosing, a broadening in immunity against drifted influ- ... dose levels suggesting dose sparing potential. However, with a ...

Optimizing target and diaphragmatic configuration, and dosimetric ...

Further investi- gation is warranted to explore the role of CPAP as a novel strategy for respiratory motion manage- ment. Keywords: Stereotactic ...

Airway Clearance With an Optimized Mechanical Insufflation ...

CONCLUSIONS: The optimized MI-E maneuver, applied with slow insufflation, resulted in a higher expiratory flow bias, which made the therapy more ...