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Cisplatin dosing


Standard versus fractionated high-dose cisplatin plus radiation for ...

Highlights. •. The 4-day fractionated regimen allows significantly more patients to receive a third cycle of cisplatin, with fewer dose reductions than the ...

Cisplatin Scheduling and Dosing Aspects F.E. de Jongh

Protective measures against gastrointestinal and renal toxicity enabled treatment with larger individual and cumulative doses of cisplatin resulting in more ...

Calculating the dose of cisplatin that is actually utilized in ...

For ovarian cancer patients who receive cisplatin for HIPEC at 43 °C, the AD of cisplatin can be calculated from the TD and VPretained using the ...

Cisplatin - wikidoc

FDA-Labeled Indications and Dosage (Adult). Metastatic Testicular Tumors. The usual Cisplatin Injection dose for the treatment of testicular ...

An analysis of cisplatin dosing and other clinical prognostic factors

Chemoradiation in locally advanced cervical carcinoma: An analysis of cisplatin dosing and other clinical prognostic factors · Download PDF · Cite · Set Alert ...

Optimal regimen of cisplatin in squamous cell carcinoma of head ...

Dosing schedule optimizations have looked at weekly cisplatin dosing ranging from 30 to 40 mg/m2 or daily administration from 5 to 7 mg/m2. Weekly dosing has ...

Do you cap cisplatin dose in obese patients undergoing - theMednet

Do you cap cisplatin dose in obese patients undergoing chemotherapy in germ cell tumors? Do you cap BSA at 2 or 2.2 for such patients to prevent Cisplatin ...

One cisplatin dose provides durable stimulation of anti-tumor ...

Multiple cisplatin dosing reduces the number of TAMs and DCs in the primary tumor, and enhances local PD-(L)1 immune cell positivity · Figure 2. Multiple ...

Evaluating dose of cisplatin responsible for causing nephrotoxicity

It has been reported that 20–30% of patients treated with cisplatin develop nephrotoxicity after 1 to 2 weeks of administration [1–4]. Although ...

IMFINZI® (durvalumab) Dosing & Administration for 1L ES-SCLC

1L=first line; AUC=area under the curve; EP=etoposide and either carboplatin or cisplatin; ES-SCLC=extensive-stage small cell lung cancer; IO=immuno-oncology; ...

A Randomized Controlled Trial Comparing Two Different Schedules ...

Previous studies suggest that a cumulative cisplatin dose of 200 mg/m2 might be adequate in the intensity-modulated radiation therapy (IMRT) ...

Cisplatin Accord (CISPLATIN) Solution for injection - Medsafe

It may be employed, in appropriate circumstances, in addition to other modalities, e.g. radiotherapy or surgery. 4.2. DOSE AND METHOD OF ADMINISTRATION. The ...

Cisplatin (PIM 132) - INCHEM

In larger and prolonged dosing with cisplatin the ototoxicity can be irreversible. Myelosuppression is a common problem seen as leucopenia, thrombocytopenia and ...

Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin ...

We predicted the optimal gap in BEV-PEM/CIS dosing to be 2.0 days in mice and 1.2 days in humans. Our simulations suggest that the efficacy loss ...

Hydration Methods for Cisplatin Containing Chemotherapy

Nephrotoxicity might already occur after one single dose of cisplatin. ... Cisplatin-induced nephrotoxicity (CIN) manifests as both chronic kidney ...

NRG-HN009: Cisplatin and Radiation for Advanced Head and Neck ...

Comparing two cisplatin dosing schedules combined with radiation for patients with advanced head and neck cancer. Currently Available for Patients. About This ...

Standardization of Chemotherapy and Individual Dosing of Platinum ...

Abstract. Platinum compounds represent a pharmacological class essential for the treatment of certain types of cancer. Cisplatin, carboplatin ...

SGO, FWC, and GOG-F* Communique

SGO, FWC, and GOG-F* Communique: Considerations When Treating Cervical, Vulvar, and Vaginal Cancers in the Setting of Cisplatin and Carboplatin ...

Durvalumab plus Gemcitabine and Cisplatin in Advanced Biliary ...

... dose-limiting toxicity, in a nonrandomized, single-center study, establishing proof of concept for this approach in advanced biliary tract ...

Cisplatin Uses, Side Effects & Warnings - Drugs.com

Cisplatin is given as an infusion into a vein. A healthcare provider will give you this injection. Cisplatin is sometimes given for 5 days in a ...