Development of Genome|Derived Tumor Type Prediction to Inform ...

Mutational signatures for breast cancer diagnosis using artificial ...

The accumulation of gene mutations has been linked to the progression of several cancer types in the past [32]. Breast cancer, cervical cancer, ...

How the Human Genome Project shook the world of cancer research

With all of this new and powerful genetic information, scientists were hoping to develop ... For example, about half of all melanomas – a type of ...

Primary tumor type prediction based on US nationwide genomic ...

9. Penson, A. ... Development of genome-derived tumor type prediction to inform clinical cancer care. JAMA Oncol. 2020; ...

MI_DenseNetCAM: A Novel Pan-Cancer Classification ... - Frontiers

The goal of the pan-cancer analysis was to assemble data from the separate disease projects to build a data set spanning multiple tumor types ( ...

NIH completes in-depth genomic analysis of 33 cancer types

The project focused not only on cancer genome sequencing, but also on different types of data analyses, such as investigating gene and protein ...

Deep learning-based survival prediction for multiple cancer types ...

We developed a deep learning system (DLS) to predict disease specific survival across 10 cancer types from The Cancer Genome Atlas (TCGA).

Whole-genome and transcriptome analysis enhances precision ...

(C) Genome signatures most frequently used to inform treatments, grouped by tumour type, drug class and clinical benefit for the informed ...

Genomic tumor analysis provides clinical guidance for the ...

One method of diagnosis utilizes genomics, with the inherent understanding that cancer is a genetic disease resulting from congenital or ...

Genetic and Genomic Testing for Prostate Cancer: Beyond DNA ...

These challenges include imperfect detection (eg, poor sensitivity for CNVs in low ctDNA fraction), difficulty of predicting alteration ...

Precision Cancer Classification and Biomarker Identification from ...

This research presents a comprehensive pipeline designed to accurately identify 33 distinct cancer types and their corresponding gene sets.

Site-Specific and Targeted Therapy Based on Molecular Profiling by ...

More sensitive methods for genetic testing have been recently developed. RNA sequencing analysis is one of the most widely adopted and sensitive ...

Pan-cancer proteogenomics expands the landscape of ... - Cell Press

Integration of proteomic data from tumors and genetic screen data from cell lines identifies protein overexpression- or hyperactivation-driven druggable ...

A Cancer Genome Interpreter to identify driver and actionable ...

The use of genomic information is becoming a key piece of the oncology toolkit to make informed decisions aimed to improve the management of the disease and ...

Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk ...

Several types of cancer display a familial predisposition and specific gene mutations confer a high-lifetime risk to develop the disease. During the last ...

New Test Could Predict Immunotherapy Responders

A newly identified genetic marker could potentially predict which patients are likely to respond to immunotherapy in cancer types that have ...

A New Artificial Intelligence Tool for Cancer | Harvard Medical School

ChatGPT-like AI model can diagnose cancer, guide treatment choice, predict survival across multiple cancer types · Cancer detection · Predicting ...

Radiation Response Prediction Model Based on Integrated Clinical ...

The value of the genomic profiling by targeted gene-sequencing on radiation therapy response prediction was evaluated through integrated ...

A snapshot neural ensemble method for cancer-type prediction ...

With the high-throughput next-generation sequencing technologies, cancer-specific genetic profiling is now possible. The entire genome ...

Precision cancer medicine: Concepts, current practice, and future ...

This creates different patterns (like SBS mutations of a specific type and context) of DNA damage often referred to as “genetic scars,” in the ...

Predicting the clinical status of human breast cancer by using gene ...

Recent studies demonstrate that gene expression information generated by DNA microarray analysis of human tumors can provide molecular phenotyping that ...