Emerging immunotherapy for HCC

The next evolution in expanding access to liver transplantation

Immunotherapy has revolutionised the treatment of advanced hepatocellular carcinoma (HCC). ... emerging evidence for immunotherapy across all stages of HCC.

Immunosuppressive tumor microenvironment and immunotherapy of ...

Recently, dual immune checkpoint blockade with durvalumab plus tremelimumab has also emerged as an effective treatment for advanced HCC. However ...

Advances in the Multidisciplinary Management of Hepatocellular ...

Advances in the Multidisciplinary Management of Hepatocellular Carcinoma (HCC): Strategies for Incorporating Emerging Immunotherapy Treatment Options · Program ...

Immunotherapy biomarkers for HCC: contemporary challenges and ...

Clinical management of advanced unresectable HCC has indelibly changed with the advent of immune checkpoint inhibitor (ICI) antibody therapy ...

Immunotherapy for Liver Cancer - American Cancer Society

Blocking this protein can help boost the immune response against cancer cells. This can shrink some tumors or slow their growth. Atezolizumab ...

Challenges of combination therapy with immune checkpoint ...

8,9. ICI therapy is also an attractive approach for new drug development in hepatocellular carci- noma (HCC). For anti-PD-1 ICI, both nivolumab and ...

Immunotherapy Combos Emerging in HCC Armamentarium - OncLive

Furthermore, in June 2019, the FDA granted a breakthrough therapy designation to the combination of pembrolizumab (Keytruda) and lenvatinib ( ...

Emerging role of molecular diagnosis and personalized therapy for ...

We also explore the evolving landscape of personalized therapy for HCC, including targeted therapies against key oncogenic signaling pathways, ...

Combined therapy makes headway for liver cancer

More recently, immunotherapies – treatments that spur the immune system to fight tumors – have emerged as the most effective treatments for HCC ...

Emerging data on immune checkpoint inhibitors in the neoadjuvant ...

The IMbrave150 and HIMALAYA trials established immunotherapy as the first-line treatment for patients with advanced HCC. Therefore, there has been interest ...

Immunotherapy-Based Treatments of Hepatocellular Carcinoma

Immunotherapy-based treatment combinations have recently been applied in patients with HCC, yielding positive results in clinical trials in terms of gradual ...

Combination of interventional oncology local therapies and ...

For the development of an effective HCC treatment regime, great emphasis has been dedicated to different IO local therapy mediated immune ...

Study Reveals a Trio of Immune Cells Vital in Response to Liver ...

... new approaches to cancer immunotherapy. Art Credit: Magen et al ... immunotherapy response in hepatocellular carcinoma (HCC). HCC is ...

Full article: Novel immunotherapy combinations in clinical trials for ...

The combination of immune checkpoint inhibitors is emerging as a practice changing strategy in advanced HCC, and results from ongoing clinical trials beyond ...

Atezolizumab plus Bevacizumab Combination Therapy | Liver Cancer

A New Era in Systemic Therapy for Hepatocellular Carcinoma: Atezolizumab plus Bevacizumab Combination Therapy. Subject Area: Gastroenterology , ...

Immunotherapy for children with primary liver carcinomas

Immunotherapy for children with primary liver carcinomas: Research offers new hope ... Pediatric hepatocellular carcinoma (HCC) and fibrolamellar ...

Emerging Opportunities for Combining Locoregional Therapy with ...

Immunotherapy shows great promises in solid tumors. Locoregional therapy can promote systemic immune response in hepatocellular carcinoma (HCC). The combination ...

Innovative Immunotherapies Offer Hope for Patients with Liver Cancer

Immunotherapy has transformed the HCC treatment landscape, offering new hope to patients. By targeting the TME and harnessing the immune ...

Immunotherapy for Liver Cancer | Moffitt

How does liver cancer immunotherapy work? · Atezolizumab (Tecentriq) · Durvalumab (Imfinzi) · Pembrolizumab (Keytruda) · Nivolumab (Opdivo) · Ipilimumab (Yervoy) ...

a systematic review and network meta-analysis - Sage Journals

The efficiency of various systemic therapies in advanced HCC patients with specific characteristics remains to be explored. This study revealed that the ...