EphA2 Promotes Infiltrative Invasion of Glioma Stem Cells in vivo ...

Targeting the KLF5-EphA2 axis can restrain cancer stemness and ...

... promote the migration and invasion of breast cancer cells. ... EphA2-dependent nasopharyngeal carcinoma cell invasion, metastasis and stem properties.

Oncogenic functions and therapeutic targeting of EphA2 in cancer.

In glioblastoma, as in other malignancies, cancer stem cells promote ... In addition to promoting tumor cell proliferation and invasion, EphA2 regulates host- ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

... invasion of cancer cells. Furthermore, some growth factors, such as ... Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics.

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads ...

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.Oncogene. 2014. doi ...

Recapitulating in vivo-like plasticity of glioma cell invasion along ...

Miao H, Gale NW, Guo H et al (2015) EphA2 promotes infiltrative ... glioma stem-like cells and promotes invasion. Br J Cancer 108:2516 ...

Cancer stem cells in glioblastoma - Genes Dev

PDGFRβ signaling promotes CSC survival, self-renewal, and invasion and tumor growth through downstream STAT3 activation (Kim et al. 2012). Similarly, glioma ...

Role of Eph/ephrin tyrosine kinase in malignant glioma

... glioma cell growth, migration, and invasion in vitro and in vivo. ... promotes glioma cell migration and invasion. ,. Int J Cancer. ,. 2010.

EphA2 receptor activation with ephrin-A1 ligand restores cetuximab ...

... EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene ...

EphA2 kinase in prostate cancer - Bingcheng Wang - Grantome

(2015) EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene 34:558-67.

UC San Francisco Previously Published Works - eScholarship

... glioblastoma stem cell ... EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell.

Neutralization of the CD95 ligand by APG101 inhibits...

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene 2015; 34:558–567 ...

Glioma Stem Cells as Immunotherapeutic Targets - Frontiers

... tumor sizes, inhibited invasion, and promoted tumor cell apoptosis. ... Promotes M1 Polarized Macrophages In Vivo. PloS One (2016) 11(4): ...

Ephrins and Eph receptors in stem cells and cancer

Surprisingly, administration of recombinant ligand for EphB4 inhibits tumor growth in vivo as well as growth and migration of breast cancer cells [33], ...

US20060121539A1 - Eph receptor tumor biomarkers - Google Patents

For ex vivo therapy, vectors may-be introduced into stem cells taken from ... invasion of human glioma cells. The abundant overexpression of EphA2 in ...

Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer ...

... Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma Journal Articles ... promoting significantly higher survival in vivo. Treatment ...

EphA2 is a functional entry receptor for HCMV infection of ... - PLOS

... invasion, and metastasis of tumor cells [8–10]. The antiviral ... Glioblastoma Cells Display Stem Cell-Like Phenotypes. mSphere 2017 ...