Gene expression based inference of cancer drug sensitivity

Gamma distribution based predicting model for breast cancer drug ...

proposed a Kernelized Bayesian Matrix Factorization (KBMF) based algorithm, which integrates genomic features of cell lines such as gene expression data, copy ...

A New Drug Combinatory Effect Prediction Algorithm on the Cancer ...

In order to verify the sensitive genes set of a single drug, the main factor for the synergistic or the antagonistic contribution is the ...

A novel heterogeneous network-based method for drug response ...

... gene expression and drug sensitivity data for predicting drug response. ... gene expression profile of cancer cell line based on genomic ...

Toward Explainable Anticancer Compound Sensitivity Prediction via ...

Our model is based on the three key pillars of drug sensitivity: compounds' structure in the form of a SMILES sequence, gene expression profiles ...

Genomics of Drug Sensitivity in Cancer: Home page - Cancerrxgene

We have characterised 1000 human cancer cell lines and screened them with 100s of compounds. On this website, you will find drug response data and genomic ...

Network modeling predicts personalized gene expression and drug ...

Knockdown sensitivity of each node was calculated as the sum of absolute ΔActivityKD levels for the node across all knockdown simulations, and knockdown ...

Analytical Tools - CTD² - National Cancer Institute

This method uses microarray expression profiles to reconstruct tissue-specific gene regulatory transcriptional interactions in cellular networks. This tool ...

Causal Inference in Single-cell Genomics (Yongjin Park ... - YouTube

... Cancer Research. Yongjin received a B.Sc ... From causal inference to autoencoders, memorization & gene regulation - Caroline Uhler, MIT.

Network-based identification of key master regulators associated ...

... gene expression-based biomarkers, Nature Scientific Reports 9 ... Garcia-Alonso, Transcription factor activities enhance markers of drug sensitivity in cancer, ...

Transcription Factor ELF1 Modulates Cisplatin Sensitivity in Prostate ...

... treatment of prostate cancer (PCa) patients with DDP-based chemotherapy. ... gene expression and cancer cell stemness characteristics. It was ...

Predicting Drug Sensitivity of Cancer Cell Lines via Collaborative ...

based on the omics profiles, such as gene expressions, of cancer cells. CADRE builds on the framework of collaborative filtering, which provides robustness ...

A single-cell approach to cancer mutation discovery and CRISPR ...

... based-editor technology to introduce specific cancer mutations ... cancer somatic mutations and even gene fusion rearrangements. This ...

Drug resistance gene expression and chemotherapy sensitivity ...

In conclusion, we detected drug resistance genes in different molecular subtypes of breast cancer, which may provide a clue to chemosensitivity ...

Artificial intelligence in healthcare - Wikipedia

... based on their individual genetic, molecular, and tumor-based characteristics. ... cancer drug treatment options for patients. Other projects include ...

Gene Expression–Based Algorithms For The Identification Of Drug ...

The use of gene-expression profiles rather than genomics biomarkers in therapy selection allows a wider range of patients to benefit, rather than only the ...

Genomics of Drug Sensitivity in Cancer - Cancer Dependency Map

The Genomics of Drug Sensitivity in Cancer (GDSC) project aims to identify the molecular features of cancers that predict response to anti-cancer drugs.

Single Cell Network Analysis (2024) - The Hill Times

motor control sensation and behavioral and emotional states A detailed analysis of gene expression during development of ... computational inference of gene ...