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Highly Multiplexed Digital Spatial Profiling of the Tumor ...


SpatialCells: automated profiling of tumor microenvironments with ...

SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data ... , et al. Highly multiplexed ...

Digital Spatial Profiling | Creative Bioarray

Digital Spatial Profiling (DSP) is a nondestructive method for high-plex spatial profiling of proteins and RNA from a wide variety of sample types, ...

[PDF] Multiplex Tissue Imaging: Spatial Revelations in the Tumor ...

... digital pathology: immune cells in high ... Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma ...

SpatialCells: Automated Profiling of Tumor Microenvironments with ...

Conclusions SpatialCells efficiently streamlines the automated extraction of features from multiplexed single-cell data and can process samples ...

Multiplex Digital Spatial Profiling in Breast Cancer Research

This spatial context is essential for understanding cellular interactions and tissue dynamics. Multiplex digital spatial profiling (MDSP) technologies overcome ...

PRIME PubMed | Digital spatial profiling for pathologists

The advent of "omics" technologies for high-depth tumor profiling has provided new information regarding cancer heterogeneity.

Digital spatial profiling of melanoma shows CD95 expression in ...

... high-plex Digital spatial profiling. Clin ... Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry.

Spatial Profiling Delves into the Tumor Microenvironment

“Our highly multiplexed approach was developed specifically for phenotypic analysis of FFPE and frozen tissue samples, both common sample types ...

Digital spatial profiling to predict recurrence in grade 3 stage I lung ...

Highly multiplexed digital spatial profiling of the tumor microenvironment of head and neck squamous cell carcinoma patients. Front Oncol. 2020; 10, 607349.

Spatial multi-omics analyses of the tumor immune microenvironment

... highly multiplexed spatial proteomic detection (Table 2 and Fig. ... Multiplex digital spatial profiling of proteins and RNA in fixed tissue.

SITC-NanoString Technologies Spatial Profiling Award

... Digital Spatial Profiler (DSP) to perform highly multiplexed spatial profiling of RNA and proteins. The most impactful proposal for cancer immunotherapy ...

The Pandora's box of novel technologies that may revolutionize lung ...

67. Kulasinghe, A. ... Highly multiplexed digital spatial profiling of the tumour microenvironment of head and neck squamous cell carcinoma ...

Gene Expression Profiling, Digital Spatial Profiling and Multiplex ...

... tumor, the immune response, and the TME, allowing examination of tumor-immune cell interactions at a whole tissue high level view. Multiplex ...

Spatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx ...

Multiplex digital spatial profiling of ... tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling.

NanoString GeoMx® Digital Spatial Profiling - BioChain

Designed for an all-inclusive profiling of tumor biology, the tumor ... GeoMx DSP allows for High-plex Spatial Proteomic Analysis of 96+ proteins ...

High-Plex Assessment of Biomarkers in Tumors - Modern Pathology

43. Merritt, C.R. ∙ Ong, G.T. ∙ Church, S.E. ... Multiplex digital spatial profiling of proteins and RNA in fixed tissue. Nat Biotechnol. 2020; 38:586-599.

Best Practices for Spatial Profiling for Breast Cancer Research with ...

Multiplexed Digital Spatial Profiling of Invasive Breast Tumors from Black and White Women (Omilian AR et al., Molecular Oncology 2021). In this study, GeoMx ...

Technology Overview - Propath UK

Technology Overview. Spatially resolve highly multiplexed RNA and protein markers ... high-plex digital spatial profiling Clin Cancer Res. 2020. Learn more ...

A user's perspective on GeoMx TM digital spatial profiling

GeoMxTM digital spatial profiling is a high-level multiplexing technique. ... Tumors are highly heterogeneous in their architecture ...

Highly multiplexed immunofluorescence imaging of human tissues ...

Single-cell transcriptome profiling provides a means to dissect tumor ecosystems at a molecular level and quantify cell types and states (Tirosh ...