Hypertension pharmacogenomics

Pharmacogenomics in Hypertension: Where We Stand Today

For novel genetic variants without a previously known biologic basis in blood pressure, it is crucial to validate initial findings in subsequent ...

Pharmacogenomics-based individualized treatment of hypertension ...

This study presents a case report of a premature infant with hypertension and reviews the literature on pharmacogenomics-based individualized treatment.

Hypertension genomics and cardiovascular prevention - Ng

As only very few genetic variants yielded pharmacogenetics effects individually, risk score models combining the effects of multiple polymorphisms have been ...

A Physiologic Approach to the Pharmacogenomics of Hypertension

The Pharmacogenomics of AntiHypertensive Therapy - ResearchGate

9 Thus, the goal of hypertension pharmacogenomics is to use genetic information, in addition to other pertinent clinical or demographic parameters, to select ...

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Genes implicated in the pharmacogenetics of hypertension were identified in reported African genomic studies (Ta- bles 4 and 5) and are ...

PEAR 1: Pharmacogenomic Evaluation of Antihypertensive ... - ICAPS

PEAR 1: Pharmacogenomic Evaluation of Antihypertensive Responses 1. PEAR logo. PEAR was a multicenter prospective interventional trial that included 768 ...

Hypertension pharmacogenomics: current status and future directions.

The potential clinical utility of pharmacogenomics in helping to guide antihypertensive drug therapy selection is described. The hypertension pharmacogenetics ...

Pharmacogenomics of Hypertension Treatment - ProQuest

Due to the fact that PKCα signaling seems to be involved in both mechanisms, its relationship with drug response was previously studied [12]. Polymorphism ...

Pharmacogenomics of Hypertension and Preeclampsia

Similarly, a large number of patients with preeclampsia are non-responsive to antihypertensive therapy. Pharmacogenomics may help to guide the ...

Hypertension Pharmacogenomics - OUCI

Lewington, Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective ...

Genetics of Resistant Hypertension: a Novel Pharmacogenomics ...

Abstract. Resistant hypertension (RHTN), defined as an uncontrolled blood pressure despite the use of multiple antihypertensive medications, is ...

Rational Drug Design and Optimization Strategies | Bentham Science

Extending pharmacogenomics research to include patients with hypertension receiving multiple antihypertensive drugs could help identify the genetic markers of ...

NIH Public Access - GBC Global Biotech Consulting Group

Pharmacogenomics in hypertension holds the promise of identifying genetic biomarkers for antihypertensive drug response, which might be used in the future in ...

Pharmacogenomics of Hypertension - ScienceOpen

We here report genome-wide analysis of association of 0.7M single-nucleo- tide polymorphisms (SNPs) to the different antihypertensive drug responses, and also ...

Pharmacogenomic treatment of hypertensive patients with polycystic ...

Abstract. To search for the link between the pathogenetic role of activation of the RAS in the development and progression of renal damage and the therapeu.

Pharmacogenomic Study of Selected Genes Affecting Amlodipine ...

The correlation between single nucleotide polymorphisms in selected genes (CACNA1, CACNA1D, ABCB1, ACE, ADBR2, & NOS1AP) & blood pressure ...

Pharmacogenomics in Pulmonary Arterial Hypertension: Toward a ...

Pharmacogenomics is the study of how genetic variations influence the response to drugs, by correlating gene expression with the drug's efficacy and ...

Pharmacogenetic Association of the NPPA T2238C Genetic Variant ...

... blood pressure change (6-month blood pressure − baseline blood pressure). ... Pharmacogenomics of hypertension. Curr Opin Nephrol Hypertens. 2003 ...

Treatment for Resistant Hypertension Under the Guidance of ...

Objective: To evaluate the efficacy and safety of pharmacogenomics (PGx)-guided treatment in individuals with resistant hypertension. (RH). Study Design: ...