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In Vivo Performance of Genetically Encoded Indicators of Neural ...


Directed Evolution of Key Residues in Fluorescent Protein Inverses ...

High sensitivity of genetically encoded calcium indicators (e.g., GCaMPs) combined with high resolution two-photon microscopy have provided ...

Fluorescence Imaging of Neural Activity, Neurochemical Dynamics ...

Here, we discuss the development and applications of these genetically encoded fluorescent indicators in reporting neural activity in response to various ...

New Fast Genetically Encoded Calcium Indicators: jGCaMP8

Appendix · Tsai-Wen Chen. · Hod Dana, et al., High-performance GFP-based calcium indicators for imaging activity in neuronal populations and microcompartments ...

A genetically encoded Ca2+ indicator based on circularly ...

Most notably, they enable imaging of neuronal activity in contexts ranging from dissociated neurons in vitro to brain activity in behaving ...

A bright and high-performance genetically encoded Ca2+ indicator ...

The Ca2+-dependent fluorescent response of GECIs is routinely used as a proxy for neuronal activity due to the transient changes in Ca2+ ...

Bright and sensitive red voltage indicators for imaging action ...

Genetically encoded voltage indicators (GEVIs) allow noninvasive readout of membrane potential changes of large neuronal ensembles at the single ...

Imaging Neuronal Activity During Zebrafish Behavior With a ...

Genetically encoded calcium indicators, such as cameleon, have offered the promise of noninvasively monitoring activity of neurons, but no one has ...

Characterization and Modification of Genetically Encoded Indicators ...

(2005) In vivo performance of genetically encoded indicators of neural activity in flies. J Neurosci 25: 4766-4778. 90. Romoser VA, Hinkle PM, Persechini A ...

Sensors for imaging neuronal populations in vivo

We are developing genetically-encoded voltage indicators (GEVIs) for subcellular imaging and for imaging large populations of neurons. We plan to characterize > ...

In vivo characterization of the near-infrared genetically encoded ...

Genetically encoded fluorescent calcium indicators (GECIs) allow for imaging of neuronal calcium activity with high spatiotemporal resolution.

Next-Generation Genetically Encoded Fluorescent Biosensors ...

Genetically encoded fluorescent biosensors have revolutionized the study of cell signaling and metabolism, as they allow for live-cell ...

Illuminating Brain Activities with Fluorescent Protein-Based Biosensors

Here, we review genetically encoded fluorescent sensors for imaging neuronal activities with a focus on the design principles and optimizations of various ...

Sensitive red protein calcium indicators for imaging neural activity

Genetically encoded calcium indicators (GECIs) allow measurement of activity in large populations of neurons and in small neuronal ...

Engineering Fluorescent Calcium Sensor Proteins for Imaging ...

(2008) A genetically encoded calcium indicator for chronic in vivo ... In vivo performance of genetically encoded indicators of neural activity in flies.

Fluorescence Imaging of Neural Activity.pdf - The Yulong Li Lab

Genetically encoded voltage indicators are illuminating subcellular physiology ... encoded calcium indicator for in vivo imaging. Nat ...

Improved genetically encoded near-infrared fluorescent calcium ion ...

We characterized the performance of the new NIR GECIs in cultured cells, acute mouse brain slices, and Caenorhabditis elegans and Xenopus laevis in vivo. Our ...

High-performance calcium sensors for imaging activity in neuronal ...

Calcium imaging with genetically encoded calcium indicators (GECIs) is routinely used to measure neural activity in intact nervous systems. GECIs are frequently ...

Robert Campbell: Genetically encoded indicators of neuronal activity

A plenary talk from SPIE Photonics West 2017 - http://spie.org/pw In this plenary talk, Robert Campbell of University of Albert discusses ...

Genetically encoded indicators of neuronal activity

Genetically encoded indicators of neuronal activity have diversified and improved in performance in recent years, becoming essential tools ...

University College London

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