Mitochondria are involved in bronchial smooth muscle remodeling in ...

Bronchial smooth muscle cell in asthma: where does it fit?

Beyond contractile considerations, active involvement of airway smooth muscle in bronchial remodelling mechanisms is now established. Not only ...

Mitochondria in lung disease - JCI

Bronchial (ciliated) epithelial cells, which require mitochondria for cilia beating, as well as vascular smooth muscle cells (VSMCs) and ...

Oxidative stress–induced mitochondrial dysfunction drives ...

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary ...

An imbalance in C/EBPs and increased mitochondrial activity in ...

First, it cannot be assumed that the cellular turnover of airway smooth muscle cells is significantly higher in established asthma as Trian et ...

Oxidative stress-induced mitochondrial dysfunction drives ...

... dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.

The Wnt/β-catenin signaling pathway regulates the development of ...

... associated with smooth muscle hyperplasia during airway remodeling. Of the proliferative factors in the airway smooth muscle cells ...

Oxidative stress–induced mitochondrial dysfunction drives ... - OUCI

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary ...

TGF-β Upregulated Mitochondria Mass through the SMAD2/3→C ...

Recent mechanistic studies established a link between mitochondrial dysfunction or aberrant biogenesis leading to tissue remodeling of the ...

Role of Airway Smooth Muscle Cells in Asthma Pathology

10. Mitochondria and ASM ... Mitochondria in the airway not only produce ATP but are also involved in functions such as Ca2+ buffering [102, 103, ...

Critical role of actin-associated proteins in smooth muscle ...

Airway smooth muscle cell contraction and proliferation contribute to the pathogenesis of airway hyperresponsiveness (AHR) and airway remodeling ...

Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac ...

Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac Muscle Remodeling ... associated remodeling affected the EBC and respiratory fitness.

Disruption of Mitochondrial Trafficking in Lung Epithelial Cells ...

Airflow limitation can be attributed to a combination of airway smooth muscle contraction, inflammation, edema, and fibrosis, and the presence of excess mucus ...

Full article: IL-13 Regulates Orai1 Expression in Human Bronchial ...

Increased proliferation and hypertrophy of airway smooth muscle cells (ASMCs) contribute substantially to airway remodeling in asthma. Interleukin (IL)-13 ...

Mitochondria signaling pathways in allergic asthma - Sage Journals

Epithelial, goblet, smooth muscle, and immune cells are influenced in asthma. Mitochondria of airway cells are involved in asthma ...

Bronchial smooth muscle cell in asthma: where does it fit?

Airway smooth muscle cells (aSMC) derive mainly during embryogenesis from mesenchymal precursors, in parallel with epithelial buds, and are ...

Moderate hyperoxia induces extracellular matrix remodeling by ...

... involved. Methods: We assessed the impact of ... mitochondrial dysfunction and fission. ... Airway smooth muscle in airway reactivity and remodeling ...

ERK1/2 Signaling Pathway Modulates the Airway Smooth Muscle ...

The extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway is one of the most important transduction pathways involved in the ...

Rakhee Kizhuvappat Ramakrishnan

Role of mitochondria in the development of airway remodeling ... involved in airway remodeling, the current ... Bronchial smooth muscle remodeling involves calcium- ...

Selective dysfunction of p53 for mitochondrial biogenesis induces ...

Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients ... Authors: Thomas ...

Bronchial remodeling / Publication / CRCTB

Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients.