Multiplex Digital Spatial Profiling in Breast Cancer Research

Digital Spatial Profiling for Characterization of the Microenvironment ...

For example, DSP has been used to compare the proteomic profile of breast cancer to the adjacent tumor microenvironment. This carries important ...

Digital spatial profiling of melanoma shows CD95 expression in ...

Immune checkpoint inhibitors (ICIs) have changed practice in treatment for advanced or metastatic melanoma, achieving 60% response with a ...

Technology Overview - Propath UK

How researchers are using GeoMx digital spatial profiling. Oncology. Profiling tumour heterogeneity, microenvironment and cancer stem cells; Identifying tumour ...

Applicability of Spatial Technology in Cancer Research

Multiplex digital spatial profiling of proteins and RNA in fixed tissue. ... A structured tumor-immune microenvironment in tri- ple negative ...

Redefining clinical practice through spatial profiling: a revolution in ...

This study highlights a unique response to bladder cancer therapies and suggests a promising path for spatial biology-guided clinical trials.

standR: spatial transcriptomic analysis for GeoMx DSP data

J. et al. . Multiplex digital spatial profiling ... spatial profiling for breast cancer research with the GeoMx((R)) Digital Spatial Profiler.

Advances in spatial transcriptomics and its applications in cancer ...

Applications of spatial transcriptomics sequencing technology in cancer research ... Multiplex digital spatial profiling of proteins and RNA in ...

Spatial molecular profiling of mixed invasive ductal and ... - PNAS

... Oncology (ASCO) Gianni Bonadonna Breast Cancer Research Fellowship grant to A.N. ii) Conquer Cancer ASCO Young Investigator Award to J.F, iii) National ...

Derek C Radisky - Mayo Clinic

Multiplex Digital Spatial Profiling in Breast Cancer Research: State-of-the-Art Technologies and Applications across the Translational Science Spectrum.

Digital spatial profiling to predict recurrence in grade 3 stage I lung ...

there have been only 51 reports of its use for study of the TME of naïve or treated cancers, including breast cancers (9), lung cancer (6), ...

Multiplex digital spatial profiling of proteins and RNA in fixed tissue.

Expected clustering was observed for cell lines with similar tissues of origin, including leukemia and lymphoma or breast cancers. Targets also tended to ...

Spatial transcriptomics: a new frontier in cancer research

Multiplex digital spatial profiling of proteins and RNA in fixed tissue. ... cancer determined by digital spatial gene expression profiling ...

Publication Spotlight: DSP vs. Visium: A Comparative Study in ...

Visium: A Comparative Study in Spatial Transcriptomics for Cancer Research ... Among these, the NanoString GeoMx® Digital Spatial Profiling (DSP) ...

Protein Profiling of Breast Cancer for Treatment Decision-Making

Multiplexed digital spatial profiling of invasive breast tumors from Black and White women. Mol Oncol. 2022;16:54-68. 42. Bergholtz H ...

New-generation technologies for spatial tissue analysis ...

Multiplex digital spatial profiling of proteins and RNA in fixed tissue. ... Translational Breast Cancer Research (Transl Breast Cancer Res ...

Spatial transcriptome profiling of in vitro 3D tumouroids to study ...

Multiplex digital spatial profiling of proteins and RNA in fixed tissue. ... Best. Practices for Spatial Profiling for Breast Cancer Research with the GeoMx(®) ...

Applicability of spatial transcriptional profiling to cancer research.

The NanoString GeoMx Digital Spatial Profiling (DSP) technology was commercially launched in the spring of 2019. The DSP workflow is designed to analyze spatial ...

Spatial Transcriptomics CRO Services I GeoMx platform by Nanostring

digital spatial profiling cancer immunotherapy CRO services tissue singlecell analysis. Tissue Preparation: morphological & profiling markers. Fluorescent ...

NanoString Shines Light on New IHC-Based Digital Spatial Profiler ...

... Cancer Research in April 2015, Gray said. "We proved it could work ... breast cancer markers for several aspects of disease. Initial ...

SMI 2022 - Spatial analysis techniques in multiplex single-cell imaging

... Multiplexed Ion beam Imaging (MIBI) triple-negative breast cancer dataset. Statistical framework for studying the spatial architecture of ...