Nociceptor|immune interactomes reveal insult|specific ...

Neuroimmune interactions may help explain inflammatory pain, lead ...

... nociceptors and immune cells ... Nociceptor-immune interactomes reveal insult-specific immune signatures of pain, Nature Immunology (2024).

Mapping the Human Cell Surface Interactome: A Key to Decode Cell ...

A decade of imaging cellular motility and interaction dynamics in the immune ... Dual proteome-scale networks reveal cell-specific remodeling of ...

Tracing the Origin and Progression of Parkinson's Disease through ...

This work will reveal fundamental mechanisms that account for the initiation and progression of PD, uncovering disease- and tissue-specific profiles of ...

Reconstruction of Cell-type-Specific Interactomes at Single-Cell ...

Finally, we use the set of cell-type-specific networks to evaluate whether perturbations associated with immune or brain-related disorders show cell- type- ...

The Progestin Receptor Interactome in the Female Mouse ... - eNeuro

... immune system: basic and ... specific protein interactomes of glucocorticoid and androgen receptor as revealed by proximity mapping.

Senso‐immunology: crosstalk between nociceptive and immune ...

This report indicated that TACAN is expressed in nociceptors and participates in mechanical pain-sensing. Notably, nociceptor-specific TACAN ...

Understanding the cellular interactome of non-alcoholic fatty liver ...

145. Su, T. ∙ Yang, Y. ∙ Lai, S. ... Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosis. Cell ...

Multiple Sclerosis Biomarker Candidates Revealed by Cell-Type ...

In the MS GM data sets, however, most of the upregulated genes were concentrated in immune ... To elucidate whether cell-type-specific interactome ...

Interaction mapping of endoplasmic reticulum ubiquitin ligases ...

... immune signalling and NF-kB through an interaction with CARMA3 ... reveal Cell-specific remodeling of the human interactome. bioRxiv ...

Setting the tone: nociceptors as conductors of immune responses

Interactions between nociceptors and mammalian immune cells are complex ... Nociceptor-immune interactomes reveal insult-specific immune signatures of pain ...

Neuroimmune Mechanisms Underlying Post-acute Sequelae of ...

In this study, we aimed to use our interactome platform to generate predictions on mechanisms through which specific immune cells could produce PASC-induced ...

In silico analyses of immune system protein interactome network ...

polymerase II cis-regulatory region sequence-specific DNA binding in EPAS1; lastly, ... A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

Neuro-Immune Interactions - Aligning Science Across Parkinson's

Impact on Diagnosis/Treatment of Parkinson's Disease: This work will reveal ... In PD, certain types of nerve cells can activate specific types of immune ...

Neuroimmune Communication in Health and Disease

"Sex-Specific Neural-Immune Interactions Impact Immune ... "Nociceptor Neuroimmune Interactomes Reveal Cell Type- and Injury-Specific Inflammatory Pain Pathways".

TRPV1 nociceptors are required to optimize antigen-specific primary ...

Antigen-specific antibody responses were longitudinally monitored for 28 days. Results. Here we show that TRPV1 expressing neurons are required ...

The T cell IFT20 interactome reveals new players in immune ...

Confocal imaging of antigen-specific conjugates using T cells depleted of these proteins by RNA interference showed that TCR accumulation and phosphotyrosine ...

tbad026.pdf - Oxford Academic

KEYWORDS: protein–protein interaction; target discovery; interactome; tumor immune microenvironment; ... of the specific interactions. In 2022, ...

A network view of human immune system and virus-human interaction

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Cell (2021) 184:3022–3040.e28. doi: 10.1016/j.cell.2021.04.011. PubMed ...

Motif-dependent immune co-receptor interactome profiling by ... - Lirias

... REVEALS, SCAFFOLD, Science & Technology, SIDE-CHAIN ... specific cytoplasmic interactomes of the critical immune co-receptor CD28.

Global Interactome Mapping Reveals Pro-tumorigenic Interactions of ...

Discussion. In this study, we applied the SEC-PCP-SILAC approach to identify protein interactions specific for MCF-7 cell interactome under innate NF- ...