Platelet Derived Growth Factor Receptors

Antagonism of Platelet-Derived Growth Factor Receptor in Non ...

Imatinib is also a potent inhibitor of the platelet-derived growth factor receptor. The platelet-derived growth factor receptor is crucial in ...

Quantitation of Platelet-Derived Growth Factor Receptors in Human ...

Platelet-derived growth factor (PDGF) is suggested to play an important role in the development of atherosclerosis as a migratory and mitogenic stimulus to ...

Expression of platelet-derived growth factor receptor α in peripheral ...

Share ... Platelet-derived growth factor (PDGF) induces mitosis in fibroblasts, smooth-muscle cells, and other cells. Isoforms of this factor induce ...

platelet derived growth factor receptor beta | Type III RTKs

The IUPHAR/BPS Guide to Pharmacology. platelet derived growth factor receptor beta - Type III RTKs: PDGFR, CSFR, Kit, FLT3 receptor family.

Expression of platelet-derived growth factor and its receptors in the ...

We determined the expression pattern of PDGF ligand and receptor genes in mouse kidney during development and in the mature adult kidney.

Platelet-Derived Growth Factor Receptors α and β Reporter Assay ...

Product Description. This assay utilizes proprietary human cells that have been engineered to provide constitutive expression of the Human Platelet-Derived ...

Cognitive and Socio-Emotional Deficits in Platelet-Derived Growth ...

Platelet-derived growth factor (PDGF) is a potent mitogen. Extensive in vivo studies of PDGF and its receptor (PDGFR) genes have reported that PDGF plays an ...

Platelet-derived growth factor receptors differentially inform ...

Platelet-derived growth factor (PDGF) ligands and receptors (PDGFRs) are commonly overexpressed in gliomas and initiate tumors, as proven in genetically ...

Down-regulation of cellular platelet-derived growth factor receptors ...

Well-established transregulatory loops involve platelet-derived growth factor (PDGF) down-regulation of epidermal growth factor (EGF) receptors ...

Expression of platelet-derived growth factor receptors in normal ... - JCI

PDGF-beta receptor gene and protein expression were upregulated in proliferative nephritides both at the glomerular and the interstitial level and strictly ...

Platelet-Derived Growth Factor Plays a Key Role in Proliferative ...

Re-expression of the PDGF β receptor in these cells did not improve the ability of the cells to cause PVR. In contrast, injection of cells expressing the PDGF α ...

Role of Platelet-Derived Growth Factors in the Testis

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are prototypes of growth factors and receptor tyrosine kinases involved in animal deve.

Commentary Signal transduction by the receptors for platelet ...

Platelet-derived growth factor CPDGF) is a connective tissue cell mitogen that originally was purified from human platelets, but recently ...

Platelet-derived growth factor receptor-α: a novel therapeutic target ...

The presence of PDGFRα, as well as activated PDGFRα in HCC in >70% of patients and its relationship to proliferation in liver development and other tumors, ...

PDGF receptor interaction activates bone marrow–derived ...

Our studies demonstrate that platelet-derived growth factor (PDGF), secreted by CLL cells, activated MSCs via its interaction with the PDGF receptor (PDGFR) ...

Discovery of Potent and Orally Bioavailable Platelet-Derived Growth ...

Platelet-derived growth factor receptors (PDGFRs) are now considered promising targets for the treatment of osteosarcoma.

QuickGO::Term GO:0005017

Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.

Platelet Derived Growth Factor Receptors (PDGFRs) and Their ...

Our hypothesis is that PDGFRa and PDGFRb function differently in RA, with PDGFRa having a more homeostatic role while PDGFRb promotes a more invasive phenotype.

Mesenchymal stem cells and neovascularization: role of platelet ...

Since PDGF and VEGF-A ligands utilize similar docking sites on their respective receptors, VEGF-A binding to a PDGF receptor would be expected ...

Platelet-derived growth factor - YouTube

Platelet-derived growth factor. 6.1K views · 6 years ago ...more. University of Rochester Biochemistry (Biol252). 7.02K. Subscribe.